Zudenine is a product with moisturizing properties that is used to treat pimples and skin inflammation as a result of acne. It is generally recommended by dermatologists when acne manifests aggressively damaging the patient’s skin and face.

The use of zudenine can be supplemented with some cosmetic products that help cover blemishes caused by acne, such as low-fat gels, creams or lotions.

The rapid action on pimples and blackheads makes zudenine one of the top products recommended by dermatologists. In addition to promoting the elimination of pimples, zudenine also acts as a powerful anti-inflammatory.

What is zudenine

Zudenine is a recommended medication for the treatment of acne of any degree of severity. The main active component of zudenine is adapalene 1%, a new generation retinoid and synthetic analog of vitamin A.

Zudenine is marketed as a cream and has a mechanism of action quite similar to retinoic acid. The advantage of using this medicine is the absence of antibiotics within its ingredients, therefore it should not be confused with Zudenine Plus. This aspect allows the cream to be used for a long time without the risk of developing bacterial resistance.

Zudenine is a fairly safe alternative to the powerful, but potentially dangerous, medications developed to treat acne. In addition, it has a stable chemical structure that makes it compatible with many other acne treatments. Precisely, this structure also minimizes unwanted side effects when zudenine is applied directly to the skin.

What is zudenine or adapalene for

The main use of adapalene is in treatments as part of the fight against acne. However, zudenine is used to treat complications or conditions other than acne.

Zudenine for acne

This medicine is quite useful to cleanse the skin from the effects of acne and eliminate possible infections. Zudenine works through keratinization, thus providing an anti-inflammatory effect. Treatment with this medicine is especially effective when the first signs of acne appear. In cases of more severe acne, dermatologists, in addition to zudenine, prescribe treatments with local or internally applied antibiotics.

Zudenine for scars

Various studies have shown that the adapalene present in zudenine can regenerate acne scarred skin. The patients submitted to the regenerative treatment of the skin with adapalene showed improvements after the fourth week. However, after week 20, substantial improvements in skin texture are evident.

Zudenine for wrinkles

Adapalene, the active compound in zudenine, like all retinoids, also works against the marks of aging. To take advantage of the benefits of this anti-wrinkle medication, it is recommended to apply it directly to fine lines. Of course, an important requirement for this use is that the skin is properly groomed.

Zudenine for blemishes

Zudenine may have an abrasive effect, since peeling of the skin may occur after a short time of use. However, this effect, which could be annoying, represents an advantage in the treatment against skin blemishes. The use for these purposes is carried out by applying minimal amounts of the drug accompanied by soft localized massages. It is advisable to use zudenine under the supervision of a qualified dermatologist.

How zudenine is used

As in treatment with any medication, there is an instruction for the use of zudenine, which must be followed in detail to obtain the desired results. Zudenine should be applied before bedtime and should be allowed to work overnight.

Skin care before using zudenine

Before treatment, it is recommended to cleanse the skin with a deep-action cleansing gel, but do not dry it out. This is how the skin is optimally prepared so that the treatment has the best result.

Use a soft towel or paper towel to dry your face or skin where the zudenine will be applied. Wait a few minutes until the skin is completely dry.

How to apply zudenine

The application of zudenine is directly on the skin in small doses, which do not leave traces of its use. It is important not to apply too much to problem areas, otherwise the skin will not be breathable enough.

This medicine should not be applied to the eye or lip area, or to damaged or weakened skin. If for any reason zudenine gets into the eyes or mouth, it should be washed off immediately with lukewarm water.

In case of the presence of burning sensation or when the skin begins to peel off, the use of a moisturizer or, if necessary, prescription drugs for that condition is recommended.

Other recommendations on the use of zudenine

When used with other medications, it should be allowed to dry for one to two minutes. This avoids the risk that the cream will not remain uniform and cause a bad appearance.

It is important to avoid touching the face after application, as bacteria on the hands can reduce the effect.

During the treatment it is recommended to discontinue the use of cosmetics, as well as products that dry out the skin. Therefore, exfoliating creams, abrasive soaps and products containing alcohol should not be used.

To see the results of the treatment, dermatologists recommend applying it daily, for 6 to 7 weeks without interruption. In the event of improvements at the beginning of treatment, the use of zudenine should not be discontinued, but should continue until the indicated time is completed.

Presentations of zudenine

Zudenine is marketed in pharmacies in two presentations, as a cream and as a gel. Although the active principle is present in the same concentrations, there are some advantages of one over the other presentation.

Come to Zuden

Zudenine gel is suitable for oily skin because it allows you to deal with the typical difficulties of these skin types. In this way, the medicine can act by reducing inflammation of the skin.

Zudenina cream

Zudenine cream is recommended for treating acne in people with dry and sensitive skin. Due to its characteristics, in this type of skin, the cream medicine is perfectly absorbed, starting to act in a shorter time.

Precautions and interactions with other medications

  • There are no known interactions with other medications used topically and concomitantly with zudenine. However, it should not be used with medications that contain adapalene, other retinoids, or have the same mode of action.
  • Adapalene is essentially stable to oxygen, light, and is not chemically reactive. Furthermore, extensive studies in animals and humans have shown the absence of phototoxic or photoallergic potential for adapalene.
  • The absorption of adapalene by human skin is low, so any interaction with systemic drugs is unlikely.
  • Zudenine has a potential for mild local irritation. Therefore, the simultaneous use of abrasive, astringent or irritating agents can produce an additional irritating effect. However, anti-acne treatments such as erythromycin solutions (up to 4%) or clindamycin phosphate (1% as a base) can be used in the morning when adapalene is applied at night, as there is no mutual degradation or cumulative irritation.

Conclusion on the effects of zudenine

The effects of zudenine are visible within four to eight weeks of starting treatment. However, even though the appearance improves and the presence of acne diminishes, the treatment should not be stopped. Perseverance, patience, and discipline when fighting the terrible condition of acne pay off in definite effects with the use of zudenine.

Samantha Robson
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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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