Winstrol, is a type of anabolic steroid that is available in a couple of different preparations. This steroid has previously been used to treat angioedema, a problem that causes swelling of the face, throat, or extremities. Used often by body builders and competitive athletes, there are a number of benefits to Winstrol.

For which diseases Winstrol is prescribed

Several studies have shown that Winstrol’s main mechanism of action is its binding action with cellular androgen receptors rather than activity that is not mediated by receptors.

Winstrol is also believed to have a small measurable form of properties that are anti-progestin when it comes to the progesterone receptor. It also has a reduced affinity for glucocorticoid-binding site interactions, along with independent activity of glucocorticoid, progesterone, and androgen receptors. No notable progestogenic activity has been found caused by the use of Winstrol.

As noted above, Winstrol has a high affinity for binding to sex hormone binding globulin (SHBG). Therefore, much more of the anabolic steroid is available in the bloodstream, sending signals for muscle growth to begin.

Sex hormone binding globulin is a protein that works by binding and binding with other sex hormones found in the body, such as synthetic anabolic steroids, estrogen, and testosterone. Once the protein has attached itself to the sex hormones, it renders them useless for as long as it is bound to them. It stops sex hormones from doing their job.

Indications on how to use Winstrol

The use of anabolic steroids can be associated with serious adverse reactions, many of which are dose related; therefore, patients should be placed on the lowest effective dose possible.

Dose requirements for the continuous treatment of hereditary angioedema with anabolic steroids should be individualized based on the clinical response of the patient. It is recommended that the patient start with 2 mg, three times a day.

After obtaining a favorable initial response in terms of prevention of episodes of edematous attacks, the appropriate continuous dose should be determined by decreasing the dose at intervals of one to three months to a maintenance dose of 2 mg per day. Some patients can be successfully managed on an alternate 2 mg schedule.

Winstrol side effects

  • Hepatic: cholestatic jaundice with, rarely, liver necrosis and death. Cases of hepatocellular neoplasms and hepatic peliosis have been reported in association with long-term anabolic androgenic steroid therapy. Reversible changes also occur in liver function tests, including increased retention of bromsulfalein (BSP) and increases in serum bilirubin, glutamic oxaloacetic transaminase (SGOT), and alkaline phosphatase.
  • Genitourinary system: in men. Prepubescent: phallic enlargement and increased frequency of erections.
  • Postpubertal: inhibition of testicular function, testicular atrophy and oligospermia, impotence, chronic priapism, epididymitis and irritability of the bladder.
  • In women: clitoral enlargement, menstrual irregularities.
  • In both sexes: increased or decreased libido.
  • CNS: habituation, excitement, insomnia, depression.
  • Gastrointestinal: nausea, vomiting, diarrhea.
  • Hematological: bleeding in patients with concomitant anticoagulant treatment.
  • Breast: Gynecomastia.
  • Larynx: Deepening of the voice in women.
  • Hair: hirsutism and male pattern baldness in women.
  • Skin: acne (especially in prepubertal women and children).
  • Skeletal: premature closure of the epiphysis in children.
  • Fluids and electrolytes: edema, retention of serum electrolytes (sodium, chloride, potassium, phosphate, calcium).
  • Metabolic / endocrine: decreased glucose tolerance, increased serum levels of low-density lipoprotein and decreased levels of high-density lipoprotein, increased excretion of creatine and creatinine, increased serum levels of creatinine phosphokinase (CPK).

Winstrol contraindications

  • Male patients with known or suspected carcinoma of the breast or carcinoma of the prostate.
  • Breast carcinoma in women with hypercalcemia; Anabolic androgenic steroids can stimulate osteolytic bone resorption.
  • Nephrosis or the nephrotic phase of nephritis.
  • May cause fetal harm when administered to a pregnant woman.
  • It is contraindicated in women who are or may become pregnant. If this medicine is used during pregnancy, or if the patient becomes pregnant while taking this medicine, the patient should be informed of the potential danger to the fetus.

Winstrol cautions and warnings

Anabolic steroids can cause suppression of clotting factors II, V, VII, and X, and an increase in prothrombin time. Women should be observed for signs of virilization (deepening of the voice, hirsutism, acne, and clitoromegaly). To prevent an irreversible change, drug therapy must be stopped or the dose must be significantly reduced when mild virilism is first detected. Such virilization is common after the use of high-dose anabolic androgenic steroids.

Insulin or oral hypoglycemic dose may need adjustment in diabetic patients receiving anabolic steroids.

Information for the patient. Physicians should instruct patients to report any of the following androgen side effects:

Adult or adolescent males. Too frequent or persistent erections of the penis, appearance or aggravation of acne.

Woman. Hoarseness, acne, changes in menstrual periods, or more hair on the face.

All patients. Any nausea, vomiting, changes in skin color, or ankle swelling.

Hemoglobin and hematocrit should be checked periodically for polycythemia in patients receiving high doses of anabolic steroids. Drug interaction. Anabolic steroids can increase sensitivity to blood thinners; therefore, the dose of an anticoagulant may have to be reduced to maintain prothrombin time at the desired therapeutic level.

Drug test / laboratory interference. Anabolic androgenic steroid therapy may decrease thyroxine-binding globulin levels, resulting in decreased total serum levels of T 4 and increased resin absorption of T 3 and T 4. Thyroid hormone levels free remain unchanged and there is no clinical evidence of thyroid dysfunction.

Trademarks and presentations of Winstrol

Trademarks under which Stanozolol is marketed or has been marketed include Anaysynth, Menabol, Neurabol Caps., Stanabolic (veterinary), Stanazol (veterinary), Stanol, Stanozolol, Stanztab, Stargate (veterinary), Stromba, Strombaject, Sungate (veterinary) , Tevabolin, Winstrol, Winstrol Depot and Winstrol-V (veterinary).

More information about Winstrol

Does not convert to estrogen

This is probably the favorite benefit of Winstrol for most men. Unlike many other anabolic steroids, Winstrol does not convert to estrogen, which is one of its most important benefits. Steroids that convert to estrogen within the body can cause serious side effects for male users. Since the body does not convert estrogen to Winstrol, men need not worry about problems such as gynecomastia (the development of female breasts).

Provides quality muscle growth

Winstrol provides quality muscle growth, which is another benefit of this steroid. While other anabolic steroids only increase muscle size without causing an increase in strength, Winstrol helps build strong muscles when combined with excellent workouts.

Samantha Robson
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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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