The diphenhydramine is an antihistaminic also has the characteristic of being an anticholinergic , operating in inhibiting the actions neurotransmitter acetylcholine , which is involved in various neuroendocrine functions, parasympathetic and motor of the body.Diphenhydramine is listed as one of the first generation antihistamines having been one of the first discovered. It is also one of the most used in the world, but its acquisition and consumption , due to its adverse effects and its use as a recreational drug, require permits and prescriptions . It is applied in limited cases, other drugs are usually preferred instead.The mechanism of action of diphenhydramine consists of preventing the production of histamine , thanks to the fact that it blocks H1 receptors , which are responsible for the body’s responses to allergies, such as nasal fluids, itching, rhinitis, asthma and other reactions that, if not controlled, can endanger health or life.

But… What is diphenhydramine for?

Diphenhydramine’s main function is to prevent allergic reactions caused by histamine to various allergens. It is applied to treat severe allergy cases or where it is required to rapidly reduce the effects of histamine.

Diphenhydramine, despite being one of the oldest antihistamines, is still one of the most widely used, but not only to combat allergies , but also for its other properties, which make it a mild anesthetic and a light sleeping pill . It is a common ingredient in sleeping pills, some tranquilizers, and certain pain relievers.

It serves to:

  • Fight allergic reactions
  • Treat severe allergies
  • Sedative, analgesic and tranquilizing effects
  • Sleeping effect

It is used to combat the following allergic reactions

Diphenhydramine works to counteract symptoms that occur during an allergy, such as:

  • Irritating cough
  • Rhinitis
  • Sinusitis
  • Insomnia
  • Difficulty staying asleep
  • Asthma
  • Insect bites
  • Hay fever
  • Allergy sneezing
  • Redness of the eyes
  • Atopic dermatitis
  • Initial Parkinson’s
  • Dizziness
  • Sickness
  • Urticaria
  • Conjunctivitis
  • Vertigo
  • Extrapyramidal symptoms
  • Anaphylaxis (only after epinephrine treatment)
  • Skin allergies
  • Alergia al poland

Treat severe allergies

Diphenhydramine is an antihistamine that is used to cure severe allergies.

Diphenhydramine’s primary use is as an antihistamine. It is effective and fast-acting, which is why it is used to treat strong allergies. This drug is characterized by allowing histamine to continue to be released, and only interferes with H1 receptors to prevent it from being processed.

The diphenhydramine administered against various allergies such as skin and airways, so there ointments and lozenges with this substance. These presentations address the best way in which the drug is going to be released to begin its chemical activity, remedying those ills.

Sedative, analgesic and tranquilizing effects

Diphenhydramine has mild calming effects, because it prevents the reuptake of a neurotransmitter called serotonin . This substance is involved in the inhibition of negative emotions such as sadness, anger, depression and aggressiveness.

Diphenhydramine allows this chemical to remain available to bind to postsynaptic receptors, which helps decrease some types of depression and improves mood. Currently it is used as a local anesthetic and light sedative , especially in cases where the patient has allergies to other anesthetics.

Sleeping effect

Another very common use of diphenhydramine is as a sleep aid. This use is due to its anticholinergic properties, and by inhibiting the effects of acetylcholine it produces drowsiness . That is why many sleeping pills contain diphenhydramine, either as a main ingredient or as a supplement.

Diphenhydramine contraindications

It is recommended that the administration of diphenhydramine be under medical supervision or completely avoided in cases of people such as:

  • People sensitive to diphenhydramine
  • Girls and boys
  • Elderly patients
  • Pregnant women
  • Lactating women

Diphenhydramine Side Effects

Diphenhydramine also works for mild sedative effects.

Like other antihistamines, this drug can cause side effects, some more complicated and dangerous than others.

Common side effects caused by diphenhydramine include:

  • Drowsiness
  • Dizziness
  • Confusion
  • Dry mouth
  • Constipation
  • Nasal dryness
  • Tiredness
  • Headache
  • inappetence
  • Sexual impotence
  • Threw up

Among the most dangerous side effects that indiscriminate use of diphenhydramine can cause are:

  • Inability to urinate
  • Tachycardia
  • Hallucinations
  • Assistance
  • Delusions
  • Blurry vision
  • Suffocation
  • Seizures
  • Fainting
  • Loss of consciousness

This article is informational only and is not a substitute for professional medical opinion. Consult a doctor.

Samantha Robson
 | Website

Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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