The Pregabalin is an antiepileptic drug with similar action to that of gabapentin. It is used to treat peripheral and central neuropathic pain , epilepsy, and generalized anxiety disorder in adult patients .The mechanism of action of pregabalin is that this compound binds to an auxiliary subunit of voltage-gated calcium channels in the central nervous system (CNS).

What is the use of taking pregabalin?

Pregabalin is a drug that is responsible for the treatment of conditions in which there is an overstimulation of the central nervous system (CNS), and that result in a disabling state for patients who suffer from them.

Taking pregabalin is used to treat:

  • Peripheral and central neuropathic pain
  • Epilepsy
  • Generalized anxiety disorder

Peripheral and central neuropathic pain

Neuropathic pain is a type of painful manifestation that causes damage to the nervous system. If it occurs due to damage to the peripheral nerves, it is called “peripheral neuropathic” pain. If the pain occurs from damage to the brain or spinal cord, it is called “central neuropathic” pain.

Peripheral neuropathic pain is related to different causes:

  • Infection: by some bacteria that affect the nerves
  • Inflammation: due to the pressure of herniated discs on the nerve roots.
  • Degeneration or deterioration of the nerves due to a disease that attacks them.
  • Trauma: when the nerve suffers a cut or blow.
  • Dysfunction: simply, when another possible cause is unknown.

Central neuropathic pain is related to causes such as:

  • Central nervous system diseases
  • Traumas to the central nervous system

Pregabalin helps relieve your symptoms, such as:

  • Ardor
  • Burning
  • Electrical pain
  • Stitches
  • Pain from mechanical stimuli
  • Pain from mild stimuli


Pregabalin is responsible for regularizing episodes in patients with epilepsy, reducing their frequency and intensity. With this drug, administered according to the doctor’s instructions and the current state of the patient, it is possible to restore an acceptable quality of life to the affected person.

To assess the improvement of pregabalin treatment, a record should be kept of the frequency of the episodes and their development . In this way, it can be determined whether it is necessary to prolong the treatment or increase the dose.

Generalized anxiety disorder

Pregabalin is used to treat generalized anxiety disorder (GAD). It is possible to keep the symptoms in a range of action that does not completely affect the lifestyle of the patient. These symptoms include:

  • Difficult to focus
  • Irritability
  • Inability to relax
  • Feeling nervous
  • Feeling that the mind goes blank
  • Inability to forget a worry
  • Indecision
  • Fear of making a wrong decision
  • Perceive as threatening a large number of situations, even harmless

The generalized anxiety disorder (GAD) is a mental illness, so the patient will not be reset to the whole. However, you may have a medium quality of life. You will not be spared dealing with the symptoms, but at least they will remain to a degree, without becoming extreme.

How much can I take of pregabalin?

Pregabalin can be administered to the patient depending on the condition they suffer from:

In case of neuropathic pain , treatment can be started with 150 milligrams daily , which can be divided into two or three doses. Depending on the response and tolerance of each patient, the dose can be increased to 300 milligrams per day after a period of 3 to 7 days. It will be modified as indicated by the physician and the patient’s progress.

In case of epilepsy , treatment can start with a dose of 150 milligrams daily , divided into two or three doses. Depending on the response and tolerance of the patient, the dose can be increased to 300 milligrams per day , after a week. The maximum dose allowed after one more week is 600 milligrams daily .

In case of generalized anxiety disorder (GAD), the doses can be in a range of 150 to 600 milligrams daily , dividing this in two or three doses. There should be a follow-up and an evaluation in the course of the treatment, to see if it is still required.

Pregabalin contraindications

Pregabalin is a drug that can be consumed by adults with the above conditions, and that is only contraindicated, especially for patients who are hypersensitive to the components of the formula .

Side effects of pregabalin

The most common possible side effects of pregabalin are:

  • Weight gain in diabetic patients
  • Angioedema in hypersensitive patients
  • Dizziness
  • Drowsiness
  • Cases of loss of consciousness
  • Confusion
  • Mental impairment
  • Blurry vision
  • Decreased visual acuity
  • Visual field disturbance
  • Renal insufficiency

This article is for informational purposes only and is not a substitute for professional medical opinion. Consult a doctor.


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