The prednisolone is an anti – inflammatory and antihistaminic drug belonging to the group of synthetic corticosteroids. It is a derivative of prednisone, being a secondary metabolite of this drug. It is applied in the treatment and control of autoimmune diseases and allergy symptoms.Prednisolone is listed as a glucocorticoid, that is, a corticosteroid that helps facilitate glucogenesis , which is the metabolic pathway that allows glucose biogenesis. Its mechanism of action consists of inhibiting responses of the immune system, especially the travel of leukocytes to certain regions of the body.Due to its very bitter taste , prednisolone is a difficult drug to consume for many people, such as children and people with a very sensitive palate . It can also be uncomfortable for the stomach if it is taken on an empty stomach, so in any case it is advisable to take it with enough water and with food.

What is prednisolone for?

Prednisolone is used to combat allergies, autoimmune diseases, transplant complications and, in general, control certain immune responses of the body to various triggers. For its administration, the clinical case must be studied and evaluated.

It serves to:

  • Treat ailments and conditions
  • Treat asthma, allergies, and autoimmune disorders
  • Deflate the joints
  • Improve transplant recovery

It is used to treat the following ailments and conditions

Prednisolone is used to treat disorders such as:

  • Asthma
  • Environmental allergies
  • Drug Allergies
  • Cancer
  • Ophthalmic disorders of autoimmune origin
  • Ankylosing Arthritis
  • Rheumatism
  • Drop
  • Lupus
  • Atopic dermatitis
  • Steven-Johnson syndrome
  • COPD (chronic obstructive pulmonary disease)
  • Psoriasis
  • Pemphigus
  • Loeffler syndrome
  • Addison’s disease
  • Thrombocytopenic purpura
  • Hypercalcemia
  • Sarcoidosis
  • Leukemia
  • Tuberculosis
  • Tuberculosis meningitis
  • Nephrotic syndrome
  • Crohn’s syndrome
  • Organ transplants
  • Multiple sclerosis crisis

Treat asthma, allergies, and autoimmune disorders

Prednisolone serves to inhibit responses of the immune system.

Being a corticosteroid medication, prednisolone has many effects on the immune system and its responses.

Mainly, it is responsible for inhibiting responses such as:

  • Asthma
  • Rashes
  • Runny nose
  • Eye irritation
  • Closure of the airways due to allergies
  • Symptoms of Addison’s syndrome
  • Symptoms of Crohn’s syndrome
  • Sarcoidosis symptoms
  • Thrombocytopenic purpura

For these purposes, it is used both in pills and in ointments and creams, to treat the external symptoms of psoriasis, pemphigus and atopic dermatitis.

Deflate the joints

An important use of prednisolone is as an anti-inflammatory, which is why it helps reduce joint inflammation in diseases such as:

  • Ankylosing Arthritis
  • Juvenile arthritis
  • Drop
  • Other rheumatic or joint disorders
  • Hypercalcemia

Improve transplant recovery

During many transplant procedures it is necessary to weaken the immune system so that the body does not reject the new organ or tissue . For this reason, prednisolone is used to prepare patients for this operation.

This drug is also used to treat some responses to cancer, helping to control this disease, especially in cases such as leukemia, both in adults and children.

Contraindications of prednisolone

Prednisolone helps relieve symptoms and conditions such as asthma.

Prednisolone is a drug that should be administered under medical supervision or avoided entirely, in people such as:

  • Elderly patients
  • Girls and boys
  • Patients with mental illnesses, such as depression
  • Pregnant women, especially due to a risk of miscarriage and malformations
  • Lactating women
  • Patients who are consuming other different drugs

Prednisolone is a delicate drug, only used under certain circumstances, as its indiscriminate use can cause severe side effects. The sudden stop prednisolone may also be counterproductive therefore suggest gradually leave.

Side effects of prednisolone

Being a corticosteroid, prednisolone can intervene in the functioning of the body’s metabolism and immune responses, causing other types of allergies and reactions that can even be serious in children and sensitive people.

The most common side effects of prednisolone are:

  • Dizziness
  • Allergies to prednisone or prednisolone
  • Skin rash
  • Itch
  • Humor changes
  • Soft spot
  • Changes in appetite
  • Sickness
  • Weight gain
  • Depression
  • Stomach disorders

Before any secondary reaction of prednisolone it is important to attend the doctor. It is not advisable to interrupt its consumption suddenly, as other adverse effects may appear.

This article is informational in nature and is not a substitute for professional medical opinion. Consult a doctor.

Samantha Robson
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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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