Loperamide , serves to reduce the frequency of diarrhea. It is often used for this purpose in gastroenteritis, inflammatory bowel disease, and short bowel syndrome. It is not recommended for those with blood in their stools. The drug is taken orally.

Loperamide – History

Loperamide was first made in 1969 and used medically in 1976. It is on the World Health Organization’s Essential Medicines List. Loperamide is available at a low cost. As of August 2016, the US retail cost is approximately US $ 0.31 per dose.

Loperamide – Uses

This medicine is used to treat sudden diarrhea (including traveler’s diarrhea). It works by slowing down the bowel movement. This decreases the number of bowel movements and makes the stool less watery. Loperamide is also used to reduce the amount of discharge in patients who have had an ileostomy. It is also used to treat ongoing diarrhea in people with inflammatory bowel disease.

Loperamide only treats the symptoms, not the cause of the diarrhea (such as infection). Do not use in children under 6 years of age unless directed by your doctor. See also Warning section. If your doctor has prescribed this medication, follow your doctor’s instructions and the directions on your prescription label.

Take this medication by mouth, usually after each loose stool, or as directed by your doctor. Dosage is based on your condition and response to treatment. In children, the dosage is also based on age and weight. Adults should not use more than 8 milligrams in 24 hours if they self-medicate or 16 milligrams in 24 hours if they are under the supervision of a doctor.

If you are taking the chewable tablet, take this medicine on an empty stomach. The chewable tablets should be chewed completely before swallowing.

If you use fast dissolving tablets, dry your hands before opening the blister to carefully remove a tablet. Do not push the tablet through the blister. Place the tablet on your tongue, allow it to dissolve completely, then swallow it with saliva.

Diarrhea causes dehydration. Drink lots of fluids and minerals. Watch for extreme thirst, decreased urination, muscle cramps, weakness, fainting). You may also need to switch to a bland diet during this time to reduce irritation to your stomach / intestines.

Tell your doctor if your diarrhea does not improve after 2 days, if your condition worsens, or if you develop new symptoms. If you develop blood in your stool, or if you think you may have a serious medical problem, seek medical attention immediately.

Loperamide – Side Effects

They include abdominal pain, constipation, drowsiness, vomiting, and dry mouth. It appears to be safe in lactation. It does not have significant absorption from the intestine and does not cross the blood-brain barrier when used in normal doses. It works by slowing down the contractions of the intestines.

It can cause dizziness, drowsiness, tiredness, or constipation. If your doctor has prescribed this medicine for you, remember that he or she has determined that the benefit to you outweighs the risk of side effects.

Stop taking this medicine if you have very serious side effects, including: severe constipation / nausea / vomiting, stomach / abdominal pain, uncomfortable fullness of the stomach / abdomen, fast / irregular heartbeat, severe dizziness, fainting.

A very serious allergic reaction to this drug is rare. However, seek medical attention immediately if you notice any symptoms of a serious allergic reaction, including: rash, itching / swelling (especially of the face / tongue / throat), severe dizziness, difficulty breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Loperamide – Precautions

Before taking loperamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Consult your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: stomach / abdominal pain without diarrhea, intestinal obstruction (eg, ileus, megacolon, bloating).

The rapidly dissolving tablets may contain aspartame or phenylalanine. If you have phenylketonuria (PKU) or any other condition that requires you to restrict your intake of aspartame or phenylalanine, consult your doctor or pharmacist regarding the safe use of this medication.

Antibiotics can rarely cause a serious intestinal condition (Clostridium difficile-associated diarrhea) due to a resistant type of bacteria. Symptoms include: persistent diarrhea, abdominal or stomach pain / cramps, or blood / mucus in the stool. This condition can occur weeks after antibiotic treatment has stopped. This medicine can make this condition worse.

This medication should not be used without first consulting your doctor if you have certain medical conditions. These symptoms / conditions may require other treatment before this medication can be used safely. Before using this medicine, tell your doctor or pharmacist your medical history, especially of: black / tarry stools, blood / mucus in stools, high fever, HIV infection / AIDS, liver problems, certain stomach / intestinal infections (for example, Salmonella, Shigella), a certain type of bowel disease (acute ulcerative colitis).

Loperamide can cause a condition that affects your heart rhythm (QT prolongation). QT prolongation can rarely cause severe (rarely fatal) rapid / irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require immediate medical attention.

The risk of QT interval prolongation may be increased if you have certain medical conditions or are taking other medications that can cause QT interval prolongation. Before using loperamide, tell your doctor or pharmacist about all the medicines you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation on ECG), family history of certain problems cardiac (QT). EKG prolongation, sudden cardiac death).

Low levels of potassium or magnesium in your blood can also increase your risk of QT prolongation. This risk may increase if you use certain medications (such as diuretics / “water pills”) or if you have conditions such as heavy sweating, diarrhea, or vomiting. Talk to your doctor about using loperamide safely.

This medicine may make you dizzy or drowsy. Alcohol or marijuana can make you dizzy or sleepy. Don’t drive, use machinery, or do anything that requires alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana.

Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above).

Children may be more sensitive to the effects of this drug, especially drowsiness. Children are also at higher risk for dehydration. See also Warning and How to use sections.

During pregnancy, this drug should be used only if clearly needed. Discuss the risks and benefits with your doctor.

This drug passes into breast milk, but it is unlikely to have undesirable effects on a nursing infant. Consult your doctor before breastfeeding.

Samantha Robson
 | Website

Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

Similar Posts

Leave a Reply

Your email address will not be published. Required fields are marked *