The hyoscine is a chemical whose condensed formula is C 17 H 23 NO 3 , and used as drug antispasmodic and anticholinergic . It is commercially distributed as hyoscine N-butylbromide, and is known as Buscopan . It is usually prescribed to treat gastrointestinal disorders, reducing the spasms that cause abdominal pain.Hyocine works by directly targeting the cause of pain and without disguising it, as painkillers normally do. Its mechanism of action consists of reducing the painful sensation, partially or completely eliminating the spasms . The latter are the muscular contractions that indicate that something is wrong in the body, in the abdominal region.The hyoscine or Buscapina is a semisynthetic drug, created from plant extracts obtained from the plant jimsonweed ( Datura estramonium ). This plant has antispasmodic effects, as it relaxes the smooth muscles that make up the digestive system, urinary tract, genital organs and bile ducts. Thus, colic in the abdominal area is reduced.

What is hyoscine for?

Hyoscine is a strong anticholinergic ; It blocks impulses on certain parasympathetic nerves, especially those responsible for smooth muscle contractions, which cause painful intestinal and menstrual cramps.

Hyoscine is used to:

  • Treat ailments and conditions
  • Eliminate menstrual cramps and cramps
  • Reduce intestinal pain
  • Carry out radiological examinations

The discomforts and conditions it treats are:

The drug hyoscine acts on the smooth muscles, promoting the reduction or disappearance of discomforts and conditions such as:

  • Visceral-like abdominal pain
  • Motility disorders in the intestinal tract
  • Pre and postoperative in case of surgical interventions
  • Spastic constipation
  • Pylorospasm of the infant (only under prescription and supervision of the pediatrician)
  • Acute adnexal processes, dominated by spasmodic pains
  • Spastic states of hernias
  • Post-anesthetic vomiting
  • Spasms and dyskinesias of the bile ducts
  • Spasms and dyskinesias of the urinary tract
  • Pain caused by irritating foods
  • Menstrual cramps
  • Kidney colic
  • Biliary colic
  • Liver colic

Eliminate menstrual cramps and cramps

Hyoscine is commercially known as Buscopan.

Hyoscine or Buscopan acts directly on the parasympathetic nerves , as well as on the neurorereptors of pain and prostaglandins . It is thus effective in reducing the contractions of smooth muscle tissue, thus reducing the intensity of the spasms that cause menstrual pain and kidney, liver and biliary pain.

Reduce intestinal pain

Hyoscine or Buscopan calms intestinal pain caused by consuming irritating foods, such as coffee, spicy and spicy foods, alcoholic beverages, among others.

It is also resorted to in cases of irritable bowel treatment , thanks to the fact that it reduces the pain that accompanies this condition. It is also recommended to use it in cases of gastrointestinal pain caused by stress, avoiding the condition known as “nervous stomach”, which usually appears together with abdominal pain due to muscle spasms.

Carry out radiological examinations

Hyoscine or Buscopan is used as an adjunct in the radiological examination of the digestive tract and urinary tract. This is thanks to the fact that it avoids the contraction movements of spasms . The image achieved is clearer for the observation of the internal organs in question.

Contraindications of hyoscine

It is recommended to use hyoscine or Buscopan under medical supervision if administered in people such as:

  • Girls and boys (a pediatrician should monitor the patient’s progress)
  • Elderly patients
  • Patients suffering from hypertension
  • Patients with heart failure
  • Patients with heartburn
  • Patients with fever
  • Patients suffering from ulcerative colitis
  • Patients with Down syndrome
  • Pregnant women
  • Lactating women

Hyoscine side effects

Hyoscine is a drug capable of relieving colic or spasms.

Drug interactions can occur when hyoscine N-butylbromide is combined with other drugs, such as:

  • Other antispasmodics: atropine, dicycloverine, propantheline.
  • Medicines with effects on the intestine: domperidone, promethazine, chloropheniramine, metoclopramide, diphenhydramine.

Therefore, side effects such as:

  • Incontinence (in the organs of the excretory system)
  • Dyskinesia (difficulty in bowel movement when digesting food)
  • Blood pressure decompensation
  • Increased intensity of inflammatory conditions such as colitis, if not combined with a drug that attacks the root condition.

This article is informational in nature and is not a substitute for professional medical opinion. Consult a doctor.

Samantha Robson
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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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