The Fluconazole is a drug to combat fungi . It comes from the family of trazole fungicides, which include drugs such as itraconazole, posaconazole, and voriconazole. Its mechanism of action is that it affects the enzymes involved in the formation of the cell membrane of microscopic fungi.The main blocked substance is the enzyme 14-alpha-demethylase, which is found in the hemoprotein cytochrome p450. Thus, it is possible to avoid the chemical conversion of lanosterol into ergosterol, a substance necessary for its cell membranes, and subsequently stop the reproduction of fungal beings.Generally, fluconazole is marketed in the form of pills, as it is a medicine whose administration is predominantly oral . However, there are also presentations prepared for a direct supply, intravenously , especially for patients with an advanced infestation or for preventive postoperative treatments.

What is fluconazole for?

Fluconazole is used to treat fungal infections , that is, caused by microscopic fungi. These types of invasions are called mycosis , and they will take a specific name, depending on where in the body they are located and the fungus that causes it.

Fluconazole specializes in attacking Candida yeast , except for its Candida krusei and Candida glabrata variants .

Fluconazole is used to:

  • Attack the fungus Coccidioides immitis
  • Attack the Trichophyton fungus
  • Attack the Microsporum fungus
  • Attack the Epidermophyton fungus
  • Attack the fungus Histoplasma capsulatum
  • Atacar al hongo Cryptococcus neoformans
  • Attack the Candida fungus

Attack the fungus Coccidioides immitis

The Coccidioides immitis fungus , when it consolidates its invasion, causes a disease called Coccidioidomycosis , which can cause meningitis, fever, osteomyelitis, abortion, and in advanced cases death, especially in patients with sensitive immune systems. Fluconazole is useful to counteract the presence of this fungus, especially when symptoms are just beginning.

Attack the Trichophyton fungus

Fluconazole is a powerful antifungal or antifungal.

This fungus is responsible for infections of the skin, nails and outer mucous membranes, such as:

  • He had
  • Athlete’s foot
  • Onicomicosis

Fluconazole is capable of effectively deactivating its reproduction, which is why it is one of the main drugs to treat athlete’s foot and eliminate it at its roots.

Attack the Microsporum fungus

The group of Microsporum fungi is one of those that cause the most common skin infections, such as:

  • He had
  • Dermatophytosis

These are characterized by reddish lesions on the skin and scalp, which can easily lead to baldness when treatment is not started.

Attack the Epidermophyton fungus

The Epidermophyton is a fungus associated with athlete ‘s foot, ringworm and skin infections . Fluconazole is an appropriate treatment to eliminate it radically, and thus mitigate the annoying symptoms, such as:

  • Itch
  • Irritation
  • Peeling
  • Appearance of blisters

Attack the fungus Histoplasma capsulatum

The Histoplasma capsulatum is the fungus causing histoplasmosis pulmonary or systemic, dangerous infection that can be contracted being exposed to feces of birds and bats, and a inhaling dust and dirt with spores of the fungus . Depending on the severity of the case and the chronicity of your disease, fluconazole is given as treatment.

Atacar al hongo Cryptococcus neoformans

The Cryptococcus neoformans is a leading cause of meningitis , and form propagation is through the spores contained in the stool , which in the inhaled reach the body, which reproduces and generates the disease. Intravenous fluconazole is one of the most effective and common treatments for resolving this condition.

Attack the Candida fungus

Candida infections are very common and can affect various parts of the body. Fluconazole is ideal to eliminate it due to its ability to reach areas of the body that other antifungals do not cover .

Yeasts (another name for “microscopic fungi”) belonging to the Candida group are the most common cause of infections called candidiasis that can occur in the vaginal, oral, pulmonary and systemic areas. They are generally present even in healthy people, but when the immune system is affected, they proliferate uncontrollably.

Candida yeasts even create whitish plaques on the tongue, throat, vagina, genitals, anus, wounds, and in organs such as the lungs, liver, and intestines. Candida, like other fungi, affects more patients with HIV, diabetics and with sensitive immune systems. Therefore, in severe cases fluconazole is used intravenously , for its immediate action.

Contraindications of fluconazole

Fluconazole is a drug that eliminates mycoses or fungal invasions.

The administration of fluconazole should be avoided in people such as:

  • Patients allergic or sensitive to the chemical activity of trazole fungicides.
  • Patients with liver deficiencies or previous conditions , as there is a risk of hepatotoxicity if used for a long time.
  • Patients with cardiac arrhythmias or taking cisapride , since fluconazole worsens these conditions and cisapride also; therefore, it is not advisable to take them together.
  • Pregnant and lactating women , unless the benefit outweighs the risk by the doctor.

Side effects of fluconazole

Fluconazole is a drug that attacks fungi by intervening in their cell reproduction. Therefore, the cells of animals and plant species are not affected.

The side effects that arise when taking fluconazole are:

  • Dizziness
  • Sickness
  • Headache
  • Threw up
  • Skin rash

Before any symptoms, it is essential to inform the doctor, as it can be a sign of allergy or an indicator of other diseases.

This article is informational in nature and is not a substitute for professional medical opinion. Consult a doctor.

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