The domperidone is a drug belonging to the chemical class of benzamides. It is used for two main reasons:

  • It is antiemetic: it prevents or stops nausea, vomiting and regurgitation.
  • It helps gastric motility , that is, it promotes the correct transit of food throughout the digestive system, especially in the stomach, the small intestine, and to a lesser extent in the colon.

It is responsible for selectively blocking D2 receptors in a part of the brain stem called the chemoreceptor trigger zone , whose initials are ZQG. After this block, it does not have a significant passage through the blood-brain barrier, making it a very safe drug.

What is domperidone for?

This medicine is indicated by doctors for all ages, presenting itself in suspension modalities and even as suppositories, for young children. In the latter it has been applied to reduce nausea, vomiting and regurgitation .

Domperidone is used to:

  • Relieve gastrointestinal symptoms
  • Improve transit in the digestive system

Relieve gastrointestinal symptoms

Domperidone is responsible for relieving symptoms in the digestive tract, such as nausea, vomiting and regurgitation, which in turn can cause abdominal discomfort.

Its chemical activity is optimal if it is ingested about 15 or 20 minutes before each meal , since the consumption of food hinders its absorption in the body.

This medicine is free to consume, so a prescription is not required to purchase it. However, it is advisable to go to the doctor before committing the recklessness of self-medicating.

Improve transit in the digestive system

Domperidone is used to treat stomach and intestinal problems.

Domperidone is a drug that works in two ways:

In the first instance, it acts on the brain, blocking its response in the form of nausea and vomiting. The sensations disappear and the stimulus is repressed.

On the other hand, it boosts gastrointestinal motility . This is the muscular activity that causes food to be processed in every organ of the digestive system, from the esophagus to the anus. It is about the involuntary contractions of these ducts.

Contraindications of domperidone

It is recommended to monitor the administration of this drug in people who have one or more of the following conditions:

  • Liver disease (in the liver)
  • Hypertension
  • Pregnancy
  • Kidney difficulties (in the kidneys)

This article is informative. Avoid self-medicating. Consult a doctor.

Samantha Robson
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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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