Betamesone is renowned for being used to combat itching, redness, dryness, scabbing, scaling, inflammation, and discomfort from various skin conditions. This medication is sometimes prescribed for other uses; consult your doctor or pharmacist for more information.

How should this medicine be used?

Betamethasone comes in an ointment, cream, lotion, and aerosol (spray) in various strengths for use on the skin. It is usually applied one to four times a day. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any parts you do not understand. Use betamethasone exactly as directed. Do not use more or less or use more often than prescribed by your doctor. Do not apply to other areas of your body or wrap or bandage.

Wash or soak the affected area well before applying the medication, unless it irritates the skin. Then apply ointment or cream sparingly in a thin film and rub in gently.

To use the lotion on the scalp, part the hair, apply a small amount of the medicine to the affected area, and rub it in gently. Protect the area from washing and scrub until lotion dries. You can wash your hair as usual, but not right after applying the medicine.

To apply a spray, shake well and spray over the affected area holding the container about 3 to 6 inches away. Spray for about 2 seconds to cover an area the size of your hand. Be careful not to inhale the vapors. If you are spraying close to your face, cover your eyes.

  • Avoid prolonged use on the face, in the genital and rectal areas, and in the folds and armpits of the skin unless directed by your doctor.
  • If you are using betamethasone on your face, keep it out of your eyes.
  • Do not wear tight diapers or plastic pants on children. Such use can increase side effects.
  • Do not apply cosmetics or other skin preparations to the treated area without consulting your doctor.

If your doctor tells you to cover or bandage the treated area, follow these instructions:

  • Soak the area in water or wash it well.
  • While the skin is wet, gently rub the medicine into the affected areas.
  • Cover the area with plastic wrap (such as Saran Wrap or Handi-Wrap.) The plastic can be held in place with a gauze or elastic bandage or tape on normal skin next to the treated area. (Instead of using plastic wrap, you can use plastic gloves for your hands, plastic bags for your feet, or a shower cap for your scalp.)
  • Carefully seal the edges of the plastic to ensure the wrap adheres closely to the skin. If the affected area is damp, you can leave the edges of the plastic wrap partially open or puncture the wrap to allow excess moisture to escape.
  • Leave the plastic wrap in place for as long as your doctor tells you. Plastic wraps are typically left in place for no more than 12 hours per day.
  • Cleanse the skin and reapply the medication each time a new plastic wrap is applied.
  • Call your doctor if the treated area worsens or if burning, swelling, redness, or pus draining develops.

What special precautions should I follow?

  • Tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially cancer chemotherapy agents, other topical medications, and vitamins.
  • Tell your doctor if you have an infection or if you have ever had diabetes, glaucoma, cataracts, a circulation disorder, or an immune disorder.
  • Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using betamethasone, call your doctor immediately.

What should I do if I miss a dose?

Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not apply a double dose to make up for the one you forgot.

Betamethasone can cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • Drying or cracking of the skin
  • Acne
  • Itch
  • Burning
  • Change in skin color
  • Severe skin rash
  • Difficulty breathing or swallowing
  • Wheezing
  • Skin infection (redness, swelling, or drainage of pus)
  • Euphoria
  • Depression
  • Adrenal suppression
  • Hypertension
  • Equimosis

Long-term use of this medicine on large areas of skin, broken or raw skin, skin folds, or under tight dressings can rarely cause enough corticosteroid to be absorbed to cause side effects in other parts of the body. ; for example, by causing a decrease in the production of natural hormones by the adrenal glands.

Betamethasone is also used before delivering a premature baby to help prepare the lungs for breathing. However, because betamethasone crosses the placenta, which is necessary for its beneficial effects, it can also be associated with complications such as hypoglycemia and leukocytosis in newborns exposed in utero.

What should I know about the storage and disposal of this medicine?

Betamethasone is a steroid medicine. It is used for a number of diseases including rheumatic disorders such as rheumatoid arthritis and systemic lupus erythematosus, allergic conditions such as asthma and angioedema, preterm labor to accelerate the development of the baby’s lungs, Crohn’s disease cancers such as leukemia, and together with fludrocortisone for adrenocortical insufficiency, among others. It can be taken by mouth, injected into a muscle, or applied as a cream. When given by injection.

Serious side effects include an increased risk of infection, muscle weakness, severe allergic reactions, and psychosis. Long-term use can cause adrenal insufficiency. Stopping the drug suddenly after long-term use can be dangerous. The cream generally results in increased hair growth and skin irritation. Betamethasone belongs to the glucocorticoid class of drugs. Betamethasone was approved for medical use in the United States in 1961.


Betamethasone is available in several compound forms: betamethasone dipropionate (marked as diprosone, diprolene, celestamine, Procort (in Pakistan) and others), betamethasone sodium phosphate (brand name Bentelan in Italy), and betamethasone valerate (brand name Audavate , Betnovate, Celestone, Fucibet and others). In the United States and Canada, betamethasone is mixed with clotrimazole and sold as Lotrisone and Lotriderm. It is also available in combination with salicylic acid for use in psoriatic skin conditions. In Mexico it is also sold mixed with clotrimazole and gentamicin to add an antibacterial agent to the mix.

In this way, they obtained the most complete information about betamosone, although always keeping in mind that you should consult your pharmacist friend or your family doctor.

Samantha Robson
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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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