Amlodipine , sold under the brand name Norvasc among others, is a drug used to treat high blood pressure and coronary artery disease. Although not normally recommended in heart failure, amlodipine can be used if other medications are not enough for high blood pressure or heart-related chest pain. Amlodipine is taken by mouth and has an effect for at least one day.

Amlodipino – History

Pfizer’s patent protection in Norvasc lasted until 2007; the full expiration of the patent occurred later in 2007. Several generic versions are available. In the UK, amlodipine tablets from different suppliers may contain different salts. The strength of the tablets is expressed in terms of the amlodipine base, that is, without the salts.

Therefore, tablets containing different salts are considered interchangeable. The efficacy and tolerability of a fixed-dose combination of amlodipine and perindopril, an angiotensin converting enzyme inhibitor, has recently been confirmed in a prospective, observational, multicenter trial of 1,250 hypertensive patients. The medical form comes as besilate, mesilate, or maleate.

Amlodipine was first patented in 1986 with a commercial sale that began in 1990. It is on the World Health Organization’s Essential Medicines List, the safest and most effective medicines needed in a health system. It is available as a generic drug. In the United States, a month’s supply costs less than $ 25.

Amlodipino – Usos

Amlodipine is used with or without other medications to treat high blood pressure. Amlodipine belongs to a class of medications known as calcium channel blockers. It works by relaxing blood vessels so blood flows more easily.

Amlodipine is commonly used in order to prevent types of chest pain (angina). It can help increase your ability to exercise and decrease the frequency of angina attacks. It should not be used to treat attacks of chest pain when they occur. Use other medications (such as sublingual nitroglycerin) to relieve attacks of chest pain as directed by your doctor.

How to use Amlodipine

Take this medicine by mouth, usually once a day. Use this medicine regularly to get the most benefit from it. To help you remember, take it at the same time every day. It is important to continue taking this medicine even if you feel fine. Most people with high blood pressure do not feel sick.

If used for angina, this drug must be taken regularly to be effective. It should not be used to treat angina when it occurs. Use other medications (such as sublingual nitroglycerin) to relieve an angina attack as directed by your doctor. Consult your doctor or pharmacist for more details.

Amlodipine – Side Effects

Doses should be reduced in people with liver problems and in the elderly. Amlodipine is a long-acting calcium channel blocker of the dihydropyridine type. It works in part by increasing the size of the arteries.

May cause dizziness, lightheadedness, swelling of the ankles / feet, or redness. If any of these effects persist or get worse, tell your doctor or pharmacist immediately.

To reduce the risk of dizziness and lightheadedness, get up slowly when getting up from a sitting or lying position. Remember that your doctor has prescribed this medicine for you because he or she has determined that the benefit to you outweighs the risk of side effects.

Tell your doctor right away if you have any of these unlikely but serious side effects: fast / irregular / pounding heartbeat, fainting. Although this drug is effective in preventing chest pain (angina), some people who already have severe heart disease may rarely experience worsening chest pain or a heart attack after starting this drug or increasing the dose. Seek medical attention immediately if you experience: worsening chest pain, symptoms of a heart attack (such as chest / jaw / left arm pain, shortness of breath, unusual sweating).

A very serious allergic reaction to this drug is rare. However, seek medical attention immediately if you notice any symptoms of a serious allergic reaction, including: rash, itching / swelling (especially of the face / tongue / throat), severe dizziness, difficulty breathing.

Amlodipine – Precautions

Before taking amlodipine, tell your doctor or pharmacist if you are allergic to it; or to other dihydropyridine calcium channel blockers (such as nisoldipine, nifedipine) or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Consult your pharmacist for more details.

Before using this medicine, tell your doctor or pharmacist your medical history, especially of: a certain structural heart problem (aortic stenosis), very low blood pressure, liver disease.

This medicine can make you dizzy. Alcohol or marijuana can make you more dizzy. Don’t drive, use machinery, or do anything that requires alertness until you can do it safely. Limit alcoholic beverages.

Older adults may be more sensitive to the effects of this drug, especially dizziness. During pregnancy, this drug should be used only when clearly needed. Discuss the risks and benefits with your doctor. This drug is excreted in human milk. Consult your doctor before breastfeeding.

Samantha Robson
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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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