What is the Soltrim and what is it for?

Soltrim is an antibiotic with a combination of Sulfamethoxazole and Trimethoprim which is used to treat intestinal or urinary tract infections. It is also used to treat severe cases of pneumonia when combined with other types of treatments. It has a fairly high effectiveness, due to its ability to fight gram positive germs and bacteria.

What is soltrim and what is it for?

It is a pyrimidine dihydrofolate reductase inhibitor, it is an antibacterial related to pyrimethamine. It is potentiated with sulfonamides, and the trimethoprim-sulfamethoxazole combination is the most widely used form. It is sometimes used alone as an antimalarial, to prevent malaria.

The effect of its main components of sulfamethoxazo with Trimethoprim, achieves an effect that serves to eliminate the bacteria that cause a series of infections that affect the body. The most frequent treatments are:

Urinary tract infections

Soltrim is used to treat conditions and infections of the urinary tract that are very common in people, such as cystitis, inflammation of the bladder, infection of the kidney and renal pelvis, and infection of the urethra.

Acute otitis media

Soltrim is used to treat acute otitis media in pediatric patients, most often caused by a bacterial or viral infection of the middle ear, which is usually complicated by a respiratory tract infection. It is important to note that soltrim offers advantages in this diagnosis over the use of other antibiotics.

Travelers diarrhea

This antibiotic is very effective for the treatment of traveler’s diarrhea due to susceptible strains of enterotoxigenic E. coli. Therefore, specialists recommend wearing Soltrim when traveling to risk areas.

Digestive system infections

In cases of infections related to the digestive system, such as gastroenteritis, sores on the wall of the intestine (diverticulitis), bacillary dysentery, and to treat Paratyphoid and Typhoid fever, soltrim has proven to be really effective.

Respiratory infections

Cases such as rhinitis, throat infections, infection in the lungs and trachea, have been treated successfully with Soltrim. Additionally, this drug has also been shown to have a good action in the treatment of Pneumocystis carinii pneumonia, both in children and adults.

What dose of Soltrim to take?

Depending on the patient’s condition and the severity of the disease, the doctor will indicate the dose of soltrim and how long the treatment should last. However, the treatment must be adhered to to the end, which generally includes at least 7 continuous days. In any case, self-medication with soltrim is not recommended.

Soltrim adult dose

Whether it’s UTIs, bronchitis, traveler’s diarrhea, or pneumonia, adult dosages vary. These can be indicated in suspension, pills or intravenously, from 5 days, and could last up to 14 days, depending on the severity.

Soltrim dose suspension pediatric dose

For children with urinary tract infections or acute otitis media, the recommended dose is 8 mg / kg of Trimethoprim (Soltrim) and 40 mg / kg of Sulfamethoxazole (Soltrim) for 24 hours, given in two divided doses every 12 hours for 10 days.

Other alternatives to soltrim

Like soltrim, there are other drugs capable of fighting a series of infections that attack the body, with optimal results. Here are some important references as an alternative to soltrim.

What is Bactrim for

Under the same components as soltrim (sulfamethoxazole-trimethoprim), Bactrim is positioned as one of the most important antibiotics to effectively treat infections such as: urinary tract, diarrhea, otitis media, respiratory infections, etc.

What is Loperamide for

This medicine is a derivative of piperidine with opioid properties, it is exclusively used for adults in the treatment of digestive tract infections, such as diarrhea caused by parasites, bacteria and viruses; as well as other infections of the intestinal tract.

What is trimebutine for

This medicine has proven to be very effective in treating diseases or conditions that affect the proper functioning of the entire digestive system. It is used mainly to treat vomiting, diarrhea, nausea, irritable bowel, reflux, among others.

What is hyoscine for

Hyoscine is a spasmolytic used to treat menstrual, abdominal and biliary cramps, or any other symptom related to spasmodic activity in the digestive tract.

Soltrim contraindications

The active substance in soltrim is contraindicated in some patients or people with specific medical conditions:

Patients allergic to its components

People allergic to Sulfamethoxazole and Trimethoprim should refrain from taking soltrim to treat any type of infection, as the effects can be adverse.

Pregnant women

The components of soltrim have been shown to cross the placenta, so safety in pregnant women has not been established. There is an increased risk of neonatal hyperbilirubinemia.

During lactation

It has also been proven that this drug is excreted in breast milk, so it is not suitable for consumption during this stage.

Patients with marked liver damage

Contraindicated in severe IH. Therefore, there is high caution in patients with liver parenchymal injury.

People suffering from severe kidney failure

Soltrim is contraindicated in severe renal impairment where repeated measurements of plasma concentration cannot be performed.

Soltrim with other medicines

Soltrim’s interference with folic acid metabolism can cause a depression of hematopoiesis. There is potency in the risk of nephrotoxicity with cyclosporine, antipsychotics (chlorpromazine, haloperidol), antidepressants (mipramine).

Soltrim side effects

The adverse effects that occur when taking soltrim are numerous, however, they do not always occur, and many others occur sporadically.

• Gastrointestinal disorders (nausea, vomiting, anorexia)
• Allergic skin reactions (such as rash and hives)
• Weakness, fatigue, insomnia.
• Cough, shortness of breath and pulmonary infiltrates.
• Hepatitis, liver necrosis, pancreatitis, stomatitis, glossitis, emesis.
• Arthralgia and myalgia.
• Hallucinations, depression, apathy, nervousness.
• Aseptic meningitis, seizures, peripheral neuritis, ataxia, vertigo, tinnitus, headache.
• Allergies

Warnings in the use of soltrim

Soltrim, like other medicines, should be administered according to the doctor’s prescription. It is important to note that it should only be used to treat or prevent infections that have been proven or strongly suspected to be caused by bacteria susceptible to its constituents.

This is in order to reduce the risk of developing bacteria resistant to antibiotics. In this case, it is important to have culture and susceptibility information in order to obtain an effective therapy.

This medicine, mainly because it is an antibiotic, must be administered for the entire time prescribed by the doctor, even if symptoms improve after a few days. An inappropriate pause in treatment can allow bacteria to grow and trigger a more difficult-to-control diagnosis.

Conclusion on using soltrim

Soltrim is one of the antibiotics best recommended by specialists, since it is used to treat a large number of infections of the digestive tract, respiratory system, and urinary tract, among others. Although its efficacy has proven to be very effective, it is important to keep a good control of the treatment, to consider the contraindications and side effects of it, to achieve a satisfactory result.