Pain is one of the symptoms most referred to by people on the globe, whether it be emotional or physical pain, the latter being produced by trauma, intense or postoperative exercise, this is due, as it has been known since ancient times, by substances that They are released and intervene in the pain cycle, to reduce or treat it, certain medications have been created, some of natural origin or others of synthetic origin, such as naproxen sodium, but what is naproxen sodium used for?

Naproxen sodium is a powerful drug belonging to the group of NSAIDs (Non-steroidal anti-inflammatory) recommended as an analgesic and general anti-inflammatory, as it is used to treat all types of pain, basically its action is based on the decrease of the substances that produce e they intensify the pain.

Naproxen sodium can be used for any type of acute pain such as headache, some trauma or blow, after surgery to improve the postoperative period; on the other hand, also in chronic pain such as that of nervous origin due to compression or some herniated disc, including that caused by terminal illnesses.

Its absorption is 90% through the gastrointestinal tract and its analgesic effect begins in 30 to 60 minutes, its metabolism is hepatic and its excretion is mostly (90%) through the kidney and the remaining (10%) through the bile

In the market there are several presentations of this drug, depending on the country we can find the 250 mg and the 500 mg, but what is the 500 mg and 250 mg naproxen sodium for ?

Frequent use of naproxen sodium

The difference of the aforementioned presentations lies in the concentration of the active principle in each tablet or capsule and depending on the case of pain, as long as it is consumed with the appropriate time interval, remembering that the time it takes to eliminate the drug from the organism is approximately 8 to 12 hours, that is to say that a tablet can be ingested every 8 or 12 hours depending on the frequency and intensity of the pain

  • The presentation of 250 mg of naproxen sodium is frequently used for the pathology known as rheumatoid arthritis, which is a chronic degenerative disease of the joints, as it merits continuous and prolonged use of this drug, it is indicated in low doses to avoid adverse reactions.
  • The presentation of 500 mg of sodium naproxen, contrary to what has been explained above, is used in acute pathologies, such as trauma, bursitis, tendinitis, sprains; even in pain of strong intensity like that after surgery or post-surgical pain; on other occasions it is also indicated for pain originating from nerve compression, which are not easy to manage, such as lumbar disc hernias (compression of the sciatic nerve), cervical disc herniations, both known as neuropathic pain.

Apart from the aforementioned presentations, the suppository modality can be found on the market for those people who have an inability to administer it orally or in severe postoperative pain since its absorption is much faster and more effective in this way.

Presentations available in the market

Naproxen, despite being a powerful non-steroidal anti-inflammatory drug, has been combined with other compounds to improve its pharmacological action, such as the presentation with paracetamol and the presentation with carisoprodol. But, what is naproxen sodium with paracetamol for? and What is Naproxen Sodium with Carisoprodol for?

Here are the benefits and additional uses of combining them with the above medications.

Naproxen with paracetamol

Although it is known that naproxen has great anti-inflammatory properties, it also has antipyretic properties which are less than its main action, which is enhanced when combined with paracetamol and better results are obtained in cases of not only inflammatory but also infectious clinical pictures. where the fever occurs.

Its use is recommended for the following clinical pictures:

  • Tonsillitis.
  • Rheumatic fever.
  • Retropharyngeal abscess.
  • Absceso perianal.
  • Acute cholecystitis.

Naproxen with carisoprodol

In this case we can find it together with a muscle relaxant, that is, despite its analgesic, anti-inflammatory effect, it also causes relaxation of the striated muscle fiber, which is part of the voluntary movement muscles.

Its use is recommended frequently for the following pathologies:

  • Sprains
  • Tendinitis.
  • Tenosynovitis.
  • Synovitis
  • Bursitis.
  • Muscle tears
  • Muscle contracture.
  • Torticollis.

Other trade names found in the market

Remembering that naproxen is the active principle, its commercial name will change according to the commercial house that produces it and the country where it is distributed.

  • Tacron.
  • Aleve.
  • Ratiopharm.
  • Reliefs.
  • Naproxen.
  • Antalgin.
  • Naproval.
  • Naprosyn.
  • Moment.
  • Denaxpren.
  • Lundiran.

Adverse drug reactions

As is to be expected, the drugs are substances foreign to the body, so their use could generate the unwanted response, this pattern will depend on each consumer.

Among the most important that can be found we have:

  • Headache (headache).
  • Sickness.
  • Gastritis.
  • Tachycardia.
  • Dizziness.
  • Epigastralgia.
  • Dry mouth
  • Blood dyscrasia (risk of bleeding gums, urine, or stools)

Contraindications to the use of Naproxen

Like many drugs, its use must be carried out under medical supervision and indication, since certain pathologies restrict its administration:

  • People with a known history of allergy or anaphylactic reaction to the active substance (naproxen).
  • In pregnant women, in view of the fact that the person involved is the female fetus binomial, greater caution should be exercised and it should only be consumed if the obstetrician specialist indicates it.
  • In diabetic people it should always be administered while monitoring the renal function of the patient, since in case their underlying pathology over time decreases the filtration of the minor.
  • In the case of people who suffer from chronic kidney disease in which the elimination of the drug is made in the urine, therefore, its excretion is decreased and it will recirculate in the blood, increasing the risk of intoxication and adverse reactions previously mentioned.
  • People with digestive diseases known as:
    • Recent digestive bleeding.
    • Severe chronic gastritis.
    • Inflammatory bowel disease
  • Patients with recent or chronic diseases that involve a decrease in platelets, since the use of the drug would cause an increased risk of bleeding, such as:
    • Dengue.
    • Thrombocytopenic purpura.
  • Patients with liver disease that may intervene with drug metabolism, such as:
    • Hepatitis A.
    • Hepatitis B.
    • Hepatitis C.
    • Alcoholic liver cirrhosis.
    • Primary biliary cirrhosis.

Interactions with other medications

It should always be taken into account that other frequently used medications are consumed by the person who is going to ingest the medication, since it has been shown that antihypertensive medications decrease the action of naproxen, on the contrary, aspirin taken very frequently by people older than 40 years or with heart problems increases the action of naproxen and the risk of bleeding is greater.

Finally, we hope that the article has been very useful, however, we must not forget that self-medication is never recommended and for this there are people specialized in the field of health.

Samantha Robson
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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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