The rosel is an antipyretic, antihistamine and analgesic indicated to treat symptoms of flu and the same way to attack the virus that causes the disease, is usually recommended when pictures strong or intense viral arise that cause inflammation in the nasal passages (rhinitis) and fever. It is considered an effective drug to combat diseases related to the respiratory tract.

In the next post we will tell you what rosel is, its main active components, for what symptoms its use is recommended, the mechanism of action, benefits, side effects and contraindications related to the use of the drug and many more things that you should take into account. before starting a treatment with this medicine.

Uses and indications of Rosel

Also known as amantadine, chlorphenamine or acetaminophen, it is a drug that treats excessive rhinitis and is usually recommended when there are respiratory diseases caused by adenovirus and respiratory syncytial virus (RSV) for its acronym in English.

  • It is indicated as an antipyretic, analgesic, antiallergic and decongestant of the upper respiratory tract.
  • To treat diseases such as allergic rhinitis, allergic conjunctivitis, contact dermatitis, insect bites, vasomotor rhinitis, atopic dermatitis, allergic reactions to foods, among others.
  • Group A influenza flu, treats accompanying symptoms such as muscle aches, fever, nasal congestion.
  • To treat and reduce fever caused by respiratory infections.
  • To support other medications to treat severe allergic reactions.
  • Some discomforts such as headache, neuralgia, earache and the common cold.

Active ingredients or components

The active principle of “Rosel” is amantadine hydrochloride, chlorphenamine maleate and acetaminophen, its formula is given according to the available presentation:

Each 100 ml of the medicine contains:

  • Amantadine hydrochloride 0.5 g.
  • Chlorphenamine maleate 0.02 g.
  • Acetaminophen 3 g.
  • Vehículo cbp 100 ml.

Each tablet contains:

  • Amantadine hydrochloride 50 mg.
  • Chlorphenamine Maleate 3 mg.
  • Acetaminophen 300 mg.
  • Vehicle cbp 1 tablet.

Properties of its active principles

  • Amantadine hydrochloride: it is an antiviral medicine that fights the virus that causes the disease, in this case influenza A, its mechanism of action inhibits the reproduction of viral particles, thus preventing their release.
  • Chlorphenamine maleate: it is a compound that is used in medicines to treat the symptoms of allergies, its mechanism of action is responsible for inhibiting the production of histamine in the body during an allergic process, it is an antagonist of H1 receptors and it is considered a first-generation antihistamine.
  • Acetaminophen or paracetamol: antipyretic and analgesic that acts by inhibiting the synthesis of prostaglandins in the central nervous system, its mechanism of action blocks the transmission of the painful impulse at the CNS level and acts on the hypothalamus to try to regulate the temperature and bring it to a state normal.

Recommended dose

The indicated dose varies according to the age of the patient, however, it is important to remember that a specialist should be consulted before starting any self-medication with any drug. It is advisable to start treatment in the first 48 hours of symptoms.

For adults:

  • The recommended dose is between 500 and 1000 mg every six or four hours, in case of very strong symptoms it should not exceed 4,000 mg per day.

For children under 12 and over 3 years:

  • Children from 3 to 5 years old, 5 ml every 6 or 8 hours.
  • Children from 5 to 12 years old, 10 ml every 6 or 8 hours.

What should you know before taking this medicine?

  • Consult with your specialist doctor before starting treatment, carefully read the label of other drugs you are using as they may contain the same active products, causing an accidental overdose and increasing the chances of suffering from adverse effects.
  • You should never give more than the recommended dose in a 24 hour period.
  • If you are going to carry out an allergic study or test, you must suspend the treatment, so it has been shown that some of its components can interfere with the results of the same, modifying the values ​​of the tests.
  • If you are pregnant or planning to be pregnant or breastfeeding, you should first consult with your doctor.

The drug passes to the baby through breast milk and its use in lactation is contraindicated.

Side effects

Any drug can cause unwanted effects on the body, since it is a reaction that the body produces before an infrequent external agent, this will depend solely on the ability of each organism to assimilate it.

Among the most common known reactions:

  • Tiredness.
  • Insomnia
  • Nervous breakdown.
  • Dizziness
  • Ataxia.
  • Anxiety.
  • Hallucinations
  • Confusion.
  • Heart failure.
  • Hypotension
  • Dyspnoea.
  • Dry mouth
  • Threw up.

Among the less common known reactions:

  • Seizures
  • Acne.
  • Visual disturbance
  • Leucopenia.
  • Pain and difficulty urinating.
  • Exaggerated tiredness.
  • Liver disorders
  • Neutropenia.
  • Skin rash.
  • Difficulty breathing.

Contraindications

  • In people with mental problems or illnesses.
  • People who suffer from seizures and seizures.
  • Patients with liver or kidney problems.
  • People sensitive to its active compounds.
  • In patients with high blood pressure, asthma attacks, prostatic hypertrophy, glaucoma and urinary retention.
  • The product should not be administered during pregnancy or if you are breastfeeding a baby as it is excreted through breast milk.
  • This medicine should not be consumed by children under three years of age.

Interaction with other medications and other sources

  • Increases the effects produced by depressant sedatives of the central nervous system.
  • It should not be used simultaneously with monoamine oxidase inhibitors or anticholinergics.
  • The joint use with Levodopa and Carbidopa, increases the chances of producing psychotic effects in the patient’s body.
  • Hepatotoxic drugs.
  • Do not use alcohol when using the drug, studies have shown that the effects of its components lose their action and their effective potency when mixed with it.

General precautions

  • Use with special care in patients suffering from glaucomas, arterial hypertension, prostatic hypertrophy, peptic ulcer, in patients with liver disorders and kidney problems, cardiovascular disease.
  • Do not give pills to children under 12 years of age.
  • The children’s solution should not be used in children under 3 years of age.
  • The use of Rosel can stimulate the central nervous system, leading to seizures, hypotension, excitement and cardiovascular collapse.
  • It is advisable not to drive vehicles or heavy machinery since the drug can cause drowsiness and lack of motor reaction.
  • Stop using alcohol or any psychotropic substance while you are taking the medicine.
  • Give your doctor and have a list on hand of all the types of medications you take, even include any vitamins or supplements, this will be very useful in case of an emergency or medical difficulty.

Storage and preservation

  • The product should be kept out of the reach of children, always keep in its original packaging.
  • Store the product in cool places, do not expose directly to the sun’s rays or store in humid areas, preferably keep at temperatures below 30 °.
  • Never store a medicine in the bathroom.
  • If you use the infant solution and after three months of using the product for the first time you still have it, please do not administer it and discard it.
  • When more than three months have passed from the expiration date of the drug, do not consume it.
  • Do not throw medicines in the trash as it could cause accidental ingestion on pets or children, ask at the nearest pharmacy for the plans for disposal and return of expired medicines.

In the event of an accidental overdose

If there is an accidental overdose, it is considered an immediate medical emergency situation, you should resort to the nearest health center or hospital emergency service to receive adequate treatment, on the contrary, if the person is collapsed and unconscious, call the service of emergency so that the patient is seen as soon as possible.

Some manifestations of overdose:

  • Serious symptoms: renal tubule necrosis, liver necrosis and hypoglycemic.
  • Stimulation of the central nervous system producing repeated spasms, tremors, drowsiness, seizures, hallucinations and even death.
  • Central nervous system depression (cyanosis, cardiovascular collapse, sedation alertness, apnea).
  • Other more frequent symptoms: blurred vision, vomiting, dizziness, nausea, dry mouth, feeling thirsty, sweating, euphoria, excitement, hallucinations, ataxia, tachycardia.

Thank you very much for reading us! We hope that the information provided has been very useful. Remember that you should always go to a doctor and avoid self-medication, otherwise the side effects may outweigh the benefits.

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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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