The piroxicam is an antiinflammatory having the ability to decrease the production of prostaglandins and substances in the body that cause strong inflammations and pains caused by diseases such as rheumatoid arthritis or osteoarthritis, injury after operation or in cases where other anti-inflammatories don’t work.

Piroxicam benefits

The use of this medicine is indicated to improve the symptoms of sensitivity, fever, pain, inflammation and stiffness, due to the deterioration or swelling that occurs in the lining of the joints. Its antiginous, anti-inflammatory and analgesic components manage to alleviate and effectively stop the ailments that arthritis produces.

It has the advantage of being a drug with a long-lasting plasma effect, this allows chronic or very severe joint and rheumatic pain to be controlled.

It is indicated to treat specific conditions such as the following:

  • Acute or chronic pain.
  • Inflammation in the joints from rheumatoid arthritis.
  • Menstruation pains.
  • Dolores post – operatorios.
  • Malaise and fever due to inflammation of the respiratory tract.
  • Inflammation due to the accumulation of uric acid, caused by gout attacks.
  • Affection in the musculoskeletal system, due to fibrositis.
  • Degenerative condition in the joints, due to osteoarthritis.
  • In cases of sprains, fractures, dislocations and blows.
  • Muscle aches in general.
  • Joint stiffness
  • Ankylosing spondylitis.
  • Dysmenorrhea
  • Sciatica.
  • Muscle involvement in the shoulders.
  • Low back pain

How to take piroxicam

  • Instructions should be followed as directed on the label or as prescribed by the treating physician.
  • It is recommended not to abuse the time, or the amounts of the use of this medicine.
  • The dose of the treatment must be in accordance with the condition of the disease and the patient.
  • In case the doctor indicates that you have to take this medicine for a long time, the proof of medical tests will be needed.
  • It should be stored in a cool place, at room temperature, away from heat and moisture.
  • It is important to take it at the same time every day.
  • It should only be administered orally.
  • The symptoms of improvement will begin to be felt after 8 weeks of treatment, this will depend on the magnitude of the condition.

Piroxicam presentations

  • Tablets : contains 20 milligrams of active ingredient, accompanied by lactose, sodium starch glycolate, pregelatinized starch, colloidal silica, crospovidone and magnesium stearate.
  • Dispersible tablets: each tablet has 20 milligrams of its active ingredient, along with other components such as microcrystalline cellulose, lactose monohydrate, hydroxypropyl cellulose and sodium stearyl fumarate.
  • Capsule : its content of active substance is between 10 or 20 milligrams, it also contains cornstarch, lactose monohydrate, sodium lauryl sulfate and magnesium sterate.
  • Effervescent tablets : it has 20 milligrams of its active ingredient, in addition to lactose, fumaric acid, macrogol 6000, lemon aroma, aspartame and glycine sodium carbonate.
  • Oral lyophilisate : each one has 20 milligrams of its active component, along with mannitol, anhydrous citric acid, aspartame and gelatin.
  • Sachets : its content is 191.2 milligrams, equivalent to 20 milligrams of its active ingredient. Its other components are sorbitol, colloidal silica, aspartame and citrus aroma.
  • Suppositories : suppositories have a composition of 20 milligrams their active component, in addition to suppocire AM, white wax and propyl gallate.
  • Injectable : the ampoules have 20 milligrams of active ingredient, the other ingredients are monosodium phosphate dihydrate, hydrochloric acid, benzyl alcohol, sodium hydroxide, propylene glycol, ethanol, nicotinamide and water for injection.

Piroxicam precautions

When taking this medicine the following precautions should be taken into account:

  • If the person has hypersensitivity to this medicine has suffered an asthma attack after taking it, it is recommended not to use it.
  • Using it for a long time or consuming very high doses may put you at risk of having a heart attack or severe stroke.
  • It should not be taken before or after having surgery, especially if it is related to the heart.
  • While using this treatment, intestinal or stomach bleeding may occur, in which case the treating doctor should be contacted immediately. This can happen to the elderly.
  • The doctor must be informed if the patient suffers from heart conditions or diseases, diabetes, high cholesterol, ulcer, asthma, liver or kidney problems, blood clotting, high blood pressure, fluid retention or if he is a smoker, to indicate proper treatment or if you should not use this medicine.
  • It should not be indicated in the last months of pregnancy, as it would cause serious injury to the fetus.
  • Being in menstruation period, it should not be administered, as it could cause adverse effects.
  • The use of this medicine can delay the release of eggs.
  • If you are breastfeeding, it is better to avoid it, as it passes into breast milk and can cause harm to the newborn.
  • It should not be administered in children under 18 years of age.
  • People over 70 years old should not use this medicine.

Side effects of piroxicam

It is recommended to seek medical help immediately if, while being under the treatment of this medicine, symptoms or adverse reactions such as those mentioned below occur:

Common side effects

  • Dizziness
  • Diarrhea.
  • Flatulence.
  • Acidity.
  • Rash.
  • Constipation.
  • Ringing in the ears.
  • Headache

Serious side effects

  • Unusual weight gain
  • Urticaria.
  • Fever.
  • Difficulty breathing.
  • Difficulty urinating.
  • Anemia.
  • Peeling.
  • Lack of concentration.
  • Jaundice.
  • Clay-colored or bloody stools.
  • Coughing up blood
  • Vomit that looks like coffee grounds.
  • Burning eyes.
  • Redness on the skin.
  • Pale skin
  • Vision problems.
  • Joint pains
  • Ronquera.
  • Swelling of the face, lips, tongue, and throat.
  • Swelling in the legs, feet, ankles, abdomen, hands and arms.
  • Rash or blisters on the skin.
  • Acceleration in heart rate.
  • Severe stomach pains
  • Back pains.
  • Dark or bloody urine.
  • Lack of appetite.
  • Weakness and excessive tiredness.
  • Similarity to flu symptoms.

Piroxicam use conclusion

To conclude, it can be said that this analgesic, antipyretic and anti-inflammatory drug has the ability to prevent the concentration of prostaglandins in the body, an action that is due to the inhibition of cyclooxygenase, the release of lysosomal enzymes and the migration of leukocytes towards areas of inflammation. This occurs in response to injuries or illnesses that cause severe pain and inflammation, which, thanks to this active component, are effectively relieved.

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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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