We usually hear about the benefits and uses of Pinaverium Bromide . Here we tell you all the details.

Pinaverium Bromide – What is it

Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It has been shown to relieve gastrointestinal spasms and pain, transit disturbances, and other symptoms related to motility disorders and can be considered an effective first-line therapy for patients with irritable bowel syndrome (IBS).

Pinaverium bromide (INN) is a drug used for functional gastrointestinal disorders. It belongs to a group of medicines called antispasmodics and acts as a calcium channel blocker to help restore the normal contraction process of the intestine. It is most effective when taken over a full course of treatment and is not designed for immediate symptom relief or sporadic, intermittent use.

Pinaverium bromide was first registered in 1975 by Solvay Pharmaceuticals (now a division of Abbott Laboratories), and is marketed globally under the Dicetel and Eldicet brand names. Generic pinaverio is available in South Korea under the trade name Disten and in Argentina as Nulite.

Pinaverium Bromide – Indications

It is indicated for the treatment of irritable bowel syndrome, including abdominal pain, intestinal disorders and intestinal discomfort; and treatment of symptoms related to functional disorders of the biliary tract.

Pinaverium Bromide – How does it work?

It belongs to the class of drugs called gastrointestinal calcium channel blockers. This medication is used to treat irritable bowel syndrome (IBS). Helps relieve symptoms of abdominal pain, intestinal disorders and intestinal discomfort. It works by relaxing the smooth muscle of the intestine.

Pinaverium is also used to help relieve symptoms caused by certain gallbladder disorders associated with bile secretion.

This drug can be available under multiple brand names and / or in different forms. Any specific brand of this drug may not be available on all forms.

Your doctor may have suggested this drug for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or you are not sure why you are taking this medicine, talk to your doctor. Do not stop taking this medicine without consulting your doctor.

Do not give this medicine to anyone else, even if they have the same symptoms as you. It can be harmful for people to take this medicine if their doctor has not prescribed it.

Pinaverium Bromide – How to use

The usual adult starting dose for pinaverio is 50 mg, taken 3 times a day with a glass of water during meals or snacks. The duration of treatment with this medicine depends on the reason for use. Swallow this medicine whole. Do not suck or chew the tablets.

Many things can affect the dose of a drug that a person needs, such as body weight, other medical conditions, and other medications. If you are not sure what to do after you miss a dose, contact your doctor or pharmacist.

Pinaverium Bromide – Administration and Dosage

50 mg

Each orange, circular-shaped, film-coated tablet with a slightly convex surface, debossed with “S” on one side and “50” on the back, contains 50 mg pinaverium bromide. Non-medicinal ingredients: hydrophobic anhydrous silica, magnesium stearate, microcrystalline cellulose, modified cornstarch, modified lactose and talc; Film Coating: Basic Butylated Methacrylate Copolymer, Sepisperse Dry 3203 (Hydroxypropyl Methyl Cellulose, Microcrystalline Cellulose, Anatase Titanium Dioxide and Dusk Yellow (Aluminum Lake)), Sodium Lauryl Sulfate, Stearic Acid, and Talc.

100 mg

Each orange, circular-shaped, film-coated tablet with a slightly convex surface, debossed with “S” on one side and “100” on the back, contains 100 mg of pinaverium bromide. Non-medicinal ingredients: hydrophobic anhydrous silica, magnesium stearate, microcrystalline cellulose, modified cornstarch, modified lactose and talc; Film Coating: Basic Butylated Methacrylate Copolymer, Sepisperse Dry 3203 (Hydroxypropyl Methyl Cellulose, Microcrystalline Cellulose, Anatase Titanium Dioxide and Dusk Yellow (Aluminum Lake)), Sodium Lauryl Sulfate, Stearic Acid, and Talc.

Pinaverium Bromide – Precautions

Pinaverium should not be taken by anyone who is allergic to pinaverium or any of the ingredients in the medicine.

Pinaverium Bromide – Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a drug when taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by all people taking this drug. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of the people taking this medicine. Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist can advise you on managing side effects.

  • abdominal distension
  • constipation
  • diarrhea
  • dizziness
  • drowsiness
  • dry mouth
  • feeling of fullness
  • headache
  • nausea
  • Skin allergy
  • stomach ache
  • vomiting

Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you don’t seek medical attention.

Check with your doctor as soon as possible if you experience any of the following side effects:

  • difficulty to swallow
  • acidity
  • sore throat or chest

Stop taking the medicine and seek immediate medical attention if any of the following occur:

signs of a severe allergic reaction (such as abdominal cramps, shortness of breath, nausea and vomiting, or swelling of the face and throat)

Pinaverium Bromide – Warnings

Before you start using a medication, be sure to tell your doctor about any medical conditions or allergies you may have, any medications you are taking, if you are pregnant or breastfeeding, and any other important information about your health. These factors can affect the way you should use this medicine.

Medical conditions: Pinaverium tablets contain lactose. People with galactose intolerance, Lapp’s lactase deficiency, or glucose or galactose malabsorption should discuss with their physician how this medication may affect their medical condition, how their medical condition may affect the dosage and effectiveness of this medication, and whether it is needs special control.

Throat irritation: It is strongly recommended to take the tablet with a glass of water during a meal. If more than 3 tablets are taken per day, the additional tablets should be taken at the same time with a glass of water and a snack. Do not take the tablets when you are lying down or just before going to bed.

Pregnancy: The safety of Pinaverium for use during pregnancy has not been established. Pregnant women should take this drug only if the benefits outweigh the risks.

Lactation: It is not known whether pinaverium passes into breast milk. If you are a nursing mother and you are taking this medicine, it may affect your baby. This medicine is not recommended for women who are breastfeeding.

Children: The safety and efficacy of using this medicine have not been established for children.

Samantha Robson
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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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