The pantoprazole is a proton inhibitor having the ability to reduce levels of acid produced in the stomach. Its relief action is immediate in the treatments of erosive esophagitis, Zollinger-Ellison syndrome due to excess stomach acids and heartburn symptoms.

Pantoprazole benefits

This drug is a proton pump inhibitor and works by decreasing the cells that pump acid into the stomach, reducing the amount of acid and reducing the symptoms of gastroesophageal reflux.

It is indicated for treatments related to diseases of the intestines, gastritis, formation of gastric juices that are returned to the stomach, heartburn, among others that produce a high level of acidity and unfavorable injuries.

This medicine is used to be used in the following diseases and conditions:


Caused by inflammation of the esophagus due to stomach acids and bile. Also for long-term treatments and to prevent relapse into reflux diseases due to esophagitis.

Prevention of gastroduodenal ulcers formation

Produced by the continuous use of anti-inflammatory drugs.

Functional dyspepsia

It is a food-borne indigestion with symptoms such as vomiting, pain in the upper abdomen, belching, flatulence, and nausea.


Strong burning in the stomach and pharynx from burns from stomach acids.

Gastric, peptic and duodenal ulcers

They appear in the intestine, stomach and esophagus in the form of sores due to the loss of the lining of these organs.

Hernia hiatal

It arises when the stomach pushes the diaphragm muscle up.


When the inner lining of the stomach becomes inflamed.

A preventive way of Mendelson syndrome

This is a serious condition that occurs from the aspiration of stomach acids into the lungs.

How to take pantoprazole

To properly take this drug, the following recommendations should be followed:

It should be taken only in the time prescribed by the treating doctor. The use should not be extended, nor should it be stopped earlier than indicated so that improvement is felt.

When using the use for 3 years constantly, the patient can present vitamin B12 deficiency in the organism, therefore, the doctor will have to look for alternatives to recover this condition.

In case of not seeing improvement and the symptoms are worsening, it is necessary to call the doctor immediately so that he can take action and make new indications.

It should be stored in places that are at room temperature, away from heat and moisture.

Pantoprazole Precautions

It is important before you start using this medicine, to know the warnings and precautions to avoid possible adverse conditions. Some of them are:

  • If you develop chest pain, sudden weight gain, sweating, or pain in the shoulders and arm while using this medicine, you should seek immediate medical help.
  • The doctor must know if the patient suffers from diseases such as osteoporosis, liver disease, lupus, low bone mineral density or decreased magnesium levels, to indicate the appropriate treatment.
  • High doses in people over 50 may be at risk of fractures in the spine, wrists, or hip bones.
  • If the patient needs to take NSAIDs continuously, taking this drug could develop severe stomach and intestinal complications.
  • People over 65 years of age can be affected by ulcers in the stomach and duodenum or by bleeding in the intestines and stomach.
  • If you find yourself with low levels of vitamin B12, this drug reduces its absorption and can cause negative symptoms for the body.

Side effects of pantoprazole

During the taking of this medicine, common symptoms or adverse conditions that can be serious for people may occur, in which case you should call the doctor or go to an emergency center as soon as possible. Among the most common side effects are:

Common side effects

  • Joint pains
  • Headache.
  • Excessive production of salivation.
  • Diarrhea.
  • Nasal congestion.
  • Feeling of cold symptoms.
  • Throat pain.
  • Vomiting
  • Flatulence.
  • Stomach pains
  • Sneezing
  • Rash on various parts of the body.
  • Fever.
  • Constant gas in the stomach or intestines.
  • Dizziness
  • Difficulty to sleep.
  • Sensation

Serious side effects

  • Weightloss.
  • Severe stomach pains
  • Decreased urination.
  • Low magnesium level.
  • Tremors
  • Shocks
  • Acute diarrhea with blood samples.
  • Kidney colic.
  • Confusion.
  • Anxiety.
  • Muscle cramps.
  • Bruises on various parts of the body.
  • Seizures
  • Appearance of lupus symptoms.
  • Restlessness.
  • Difficulty breathing.
  • Muscle spasms in the feet and hands.
  • Cough continues.
  • Fast heartbeat

Contraindications of pantoprazole

It is necessary to know whether or not this medicine can be taken, therefore, it is important that the doctor is informed of the existence of any disease so that he can make the appropriate prescription. Here are the most prominent contraindications:

  • It should be avoided if the person has hypersensitivity to this drug or any of its components.
  • It is not recommended for those who have severe liver deficiencies.
  • When using this medicine and the patient needs to undergo laboratory tests, the treatment must be stopped for at least 4 weeks so that the results are not altered.
  • Although this medicine is effective in treating various gastrointestinal conditions, it does not have the ability to avoid the risks of gastric cancer or some other serious disease.
  • The doctor should monitor this treatment in patients with liver and kidney diseases.
  • It should not be administered to persons under 18 years of age.
  • Its use is unfavorable in pregnant women or in case of suspicion. It is also not recommended during the lactation stage, since it has been proven that it can be passed through breast milk.
  • Alcoholic beverages are usually irritating to the digestive tract, in case of taking this drug, alcohol intake is not recommended.

Pantoprazole use conclusion

It can be concluded by saying that this excellent and effective drug is intended to improve conditions caused by gastroesophageal reflux, where the flow of the stomach directs acids in the opposite way causing heartburn, lesions in the esophagus and diseases such as gastritis, ulcers and increased of gastric acids in the stomach.

Thanks for reading

Samantha Robson
 | Website

Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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