The world advances, evolves and in turn does medicine. However, some drugs are still maintained and used today, which to the public’s preference, are the most effective. That is why today we bring the Nimesulide . This drug is known worldwide for its function and benefits, similar to other NSAIDs.

If you are wondering what Nimesulide is for , it is important that you know that it is a pain reliever and anti-inflammatory. This is used to relieve pain and fever, but it is especially used for acute conditions in the upper respiratory tract.

If you are interested in knowing in depth its use, benefits, risks, among others, we invite you to continue reading and enjoy reading.

What is Nimesulide?

Nimesulide is a drug that works as an analgesic and antipyretic. Its function, in addition to alleviating conditions in the respiratory tract, is to combat some ailments such as otitis and acute cystitis, pharyngitis and mild tendonitis.

It is classified as an NSAID drug, because it belongs to the group of non-steroidal anti-inflammatory analgesics. This drug is also known as a selective COX-2 inhibitor, having the characteristic of producing a minor impact on gastrointestinal damage.

Indications of Nimesulide

A drug such as Nimesulide and other COX-2 selectives are necessary to achieve a calming effect against the pain of gastric diseases, for example, gastric ulcers and for people who have a treatment with anticoagulants.

Its consumption is recommended in these cases, due to the side effects caused by analgesics such as ibuprofen or diclofenac.

One benefit that its action offers us is that in patients with anticoagulant treatment there is a lower risk of causing side effects.

Other illnesses that it can treat are:

• Menstrual pain.
• Dental pain.
• Gynecological disorders.
• Surgical interventions.

What to take into account before consumption?

Despite being a non-steroidal drug, it is recommended to take into account the following warnings:

• In children, since it causes liver damage in their body.

Important: Due to the damage it can cause to children, in some countries the use of this product was prohibited. In these countries, sale to the public is regulated and it is only administered to patients who are of legal age. For their part, children can consume it exclusively with a medical authorization.

• In pregnant and lactating women, no alterations have been found, but they should exercise caution when consuming the drug.

Presentations and recommended dose

Nimesulide is administered orally for greater, rapid and extensive absorption of its properties. It reaches the maximum peak after three hours of consumption. Its use is recommended during or after each meal.

Its process begins by binding with 95% of plasma proteins. Then the drug is metabolized in the liver, but especially to a derivative known as 4-hydroxy, with this metabolites are secreted, preferably 80% by the kidneys.

To culminate, the delivered doses of this drug are recovered by 25% in the urine.

Presentations

Nimesulide comes in three forms: tablets, suspension, and suppositories.

• Suspension: the suspension or 5ml syrup presentation is equivalent to 50mg, so consumption should be 10ml daily to meet the recommended 100mg and to obtain the expected results and benefits.
• 100mg: the tablets come in 100mg presentations with a content of 10 or 20 tablets. To avoid secondary problems, it is recommended that the dose to be consumed daily be authorized and indicated by your doctor. Not all bodies respond the same.
• Third, there are some treatments in which high doses are necessary, for example, doses of 100mg every twelve hours (12hrs). There are other treatments that can increase the amounts up to 200mg.

Mostly it is suggested that the dose does not exceed 200mg in order to avoid side effects, the amount will always depend on the symptoms that the patient presents.

Dose

• In adults, it is best to consume between one to two pills, every twelve hours (12hrs) and should not exceed 7 days of treatment. This will depend on what your doctor tells you after your tests.
• In the most veteran of the house (elderly), it is not recommended to consume twice a day and that is greater than a 100mg tablet. If your kidney condition and treatment allow, he or she can use that amount.
• We already know that the product in children is prohibited. But if the treatment allows it, it is commonly that he is given 3 to 5mg / kg divided into two doses; This should be used strictly in the pediatric presentation, either in syrup or drops.
• There are cases, such as dysmenorrhea, which authorizes the patient to consume one tablet every twelve hours (12hrs), for a period of 10 days. Its consumption begins between the first three to five days of the beginning of the bleeding.
• For its part, the gel presentation must be applied twice a day to the affected area.

Side effects

People who suffer from any of these conditions should avoid its consumption:

• Allergy or hypersensitivity to NSAIDs.
• People with liver damage or severe kidney damage. Nimesulide produces alterations in the conditions.
• Heart conditions.
• Other side effects that may occur are: diarrhea, flatulence, vomiting, itching, sweating, dizziness, hypertension, edema and constipation.

All this will depend on the dose that is consumed. But a short treatment is recommended, as the effect falls on the liver. In the same way, it is important to consult the doctor for more information avoiding self-medication. We hope that the reading has been pleasant and very useful. Thanks for visiting us!