The metoclopramide is a gastrokinetic and antiemetic excellent, having as active ingredient the metoclopramide hydrochloride. It has a remarkable variety of uses and applications in pharmacological therapy, mainly as an adjunct in gastrointestinal treatments.

By preserving these multifaceted utilities, it can be recommended for the use of gastritis, gastric and esophageal reflux, as well as to treat symptoms such as nausea and avoid vomiting, improving and preserving gastrointestinal transit.

Metoclopramide is indicated mainly as a drug with antiemetic action, inhibiting nerve signals from the digestive tract, acting in areas of the central nervous system thus eliminating nausea, if you want to know more about the effects of metoclopramide I invite you to stay in this article.

Metoclopramide frequent uses

As a gastrokinetic and antiemetic, it can be used to alleviate a large part of gastroesophageal symptoms on the one hand, and on the other it is capable of temporarily relieving or completely eliminating the sensation of nausea and even vomiting if present, including also those that occur in the postoperative period.

As less frequent uses or strictly medical-surgical uses, it is applied to improve praxis in endoscopy by working as an analgesic, optimizing the results in gastrointestinal radiography and combating nauseous desire in various therapies such as radiotherapy, chemotherapy, among others.

Among the most frequent doubts there is the functionality of its various presentations, but the doubts are always the same. What is metoclopramide 10mg for? Either in its other presentations, in drops or tablets.

Metoclopramide tablets

It is used mainly to be able to carry out the treatment at home, where the patient, understanding that they tolerate ingesting it orally, can disperse the sensations of nausea and stop vomiting if it presents, thus avoiding returning to hospitalization, a little water will be enough to ingest it.

It is important to remember that in this presentation its use is not recommended for lactose intolerant patients, since it has small doses of this disaccharide.

Metoclopramida de 10mg.

The specific 10mg tablet presentation was designed to complete the treatment in adults with intervals of 8 hours between each intake, fulfilling a total of 3 tablets a day, until completing the treatment previously indicated by the health specialist under medical prescription.

Metoclopramide drops

This presentation is used like many drugs of this type, for use in children under 5 years of age and in some conditions of diabetic patients, the main objective is to avoid vomiting and that the infant does not fall into a dehydration picture that leads to worsening of the clinical prognosis.

Other uses of metoclopramide

  • It manages to optimize the slow emptying that people with diabetes can suffer.
  • Control nausea and vomiting caused by chemical therapy, radiation or postoperative.
  • It manages to clean the intestinal contents preparing it to undergo certain medical-surgical procedures, such as endoscopies and X-rays.
  • Its use is recommended in cases of hiatal hernia and paralysis of the stomach and esophagitis.
  • Fight gastroesophageal reflux disease. (GERD)

Diseases treated with metoclopramide

This list summarizes the main diseases that can be treated with metoclopramide:

  • Nausea and vomiting
  • ERGE
  • Migraine
  • Gastroparesis
  • Hernia hiatal

Use of metoclopramide

As a powerful drug and used only under medical prescription, it achieves great results when used properly, among its purposes we have:

  • Symptomatic prophylaxis in the aforementioned diseases.
  • Later use in surgical interventions to increase intestinal kinetics.
  • Prevent collapse in intestinal motility due to hiatal hernia.
  • It is used as a collaborator in radiological examinations.
  • It is recommended in diabetic patients with gastroparesis.

Possible side effects

It is possible to categorize the side effects that the excessive or contraindicated use of metoclopramide may entail according to the area or system it affects, among these we have:

  • CNS: It can cause asthenia , decay, lassitude, severe headache, dizziness, fatigue and can less likely cause dementia and depressive states.
  • Parkinsonian symptoms: poker face facies, bradykinesia, involuntary and uncontrollable movements of the tongue, face, mouth, hands, feet, trunk and hips.
  • Endocrine system disorders: amenorrhea, hyperprolactinemia, galactorrhea, elevated aldosterone with high fluid retention.
  • Cardiovascular disorders: It is very contradictory and can be closely linked to the condition that the person has, the signs and symptoms being highly variable, ranging from hypotension to hypertension, arrhythmias, and tachycardia with tachypnea to bradycardia with bradypnea.
  • It is good to remember that one of the effects that metoclopramide causes is to inhibit dopamine secretion, converting adrenergic and noradrenergic signals into powerful transmitting neuronsignals, causing serious problems in hypertensive patients.
  • Enterogastric reactions: delayed intestinal transit, nausea, primary type diarrhea.
  • Motor maladjustments: shivering, restlessness, agitation.

Metoclopramide warnings and contraindications

The following arguments are for prevention and basic knowledge of the subject, we recommend that all the reading public always have prior consultation with a certified health professional doctor, in order to have a correct use and management of this drug.

  • During the gestation period, it is advisable to replace the drug with another drug, and only take it if the occasion is necessary under medical prescription.
  • In the lactation period, many schools and medical texts differ in prohibiting or substituting the drug, since although it does not affect breast milk, the newborn may present some type of allergic reaction so the mother should immediately suspend the treatment.
  • Be very careful when maintaining metoclopramide treatment in hypertensive patients due to its high catecholinergic activity.
  • Do not self-administer this drug without prior medical authorization and, in turn, maintain the correct doses to be used.
  • Do not keep the drug sheltered in humid places or temperatures above 30 degrees.
  • Metoclopramide is contraindicated for conditions such as mechanical obstruction, gastrointestinal bleeding, and perforation, that is, conditions that worsen with increased gastrointestinal motility.

Conclusion of the use of metoclopramide

As closure points, it is understood that this product is a powerful gastrokinetic and antiemetic, capable of controlling neuronal neurotransmitter signals and preventing the sensation of nausea and vomiting, also used as postoperative treatment and as drug prophylaxis.

It can affect various systems as a side effect and therefore you must have a lot of judgment when consumed, so we insist on prior control with the health professional before consumption, remember that what matters most is your health.

We are glad that you have enjoyed this article to the end. Thanks for reading!

Samantha Robson
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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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