Losartan is an angiotensin receptor blocker (ARB) that blocks a substance that causes blood vessels to constrict. Sold under the brand name Cozaar, it is used to treat high blood pressure (hypertension). It is also used to lower the risk of stroke in some patients with heart disease.

Losartan – Function

By relaxing the blood vessels, Losartan helps a person maintain a lower blood pressure, increasing the supply of oxygen and blood to the heart. Losartan is also used to delay long-term kidney damage in people with type 2 diabetes, and is sometimes used to treat congestive heart failure.

Losartan was the first angiotensin receptor blocker to be sold after its approval by the Food and Drug Administration (FDA) in 1995.

Losartan – Precausiones

Important information

Do not use it if you are pregnant. Stop use and tell your doctor immediately if you become pregnant. Losartan can cause injury or death to an unborn baby if you take the drug during your second or third trimester. Use an effective method of birth control.

You should not use this medicine if you are allergic to losartan.
If you have diabetes, do not use losartan together with any medicine that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).

In rare cases, losartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness, especially if you also have a fever, unusual tiredness, and dark-colored urine.

To make sure losartan is safe for you, tell your doctor if you have:

  • kidney disease;
  • liver disease;
  • congestive heart failure;
  • lack of balance in electrolytes (low level of K, that is potassium in the blood); or if you are dehydrated

FDA pregnancy category D. Do not use if you are pregnant. Stop use and tell your doctor immediately if you become pregnant. Losartan can cause injury or death to an unborn baby if you take the drug during your second or third trimester. Use an effective method of birth control.

It is not known whether losartan passes into breast milk or if it could harm a nursing baby. You should not breastfeed while using this medicine.

Losartan – Administration

Take losartan exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You can take losartan with or without food. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than normal. You can easily become dehydrated while taking this medicine, which can lead to very low blood pressure or a serious loss of electrolyte balance.

Your blood pressure will need to be checked often. Visit your doctor regularly. It may take 3 to 6 weeks for losartan before your blood pressure is under control. For best results, keep using the medication as directed. Talk to your doctor if your symptoms do not improve after 3 weeks of treatment.

If you are being treated for high blood pressure, keep using this medicine even if you feel fine. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Losartan – Uses

Losartan is used to treat high blood pressure (hypertension) and to help protect the kidneys from damage caused by diabetes. It is also used to reduce the risk of stroke in patients with high blood pressure and an enlarged heart. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Losartan is in a class of medications called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so blood flows more easily.

Read the Patient Information Leaflet, if available from your pharmacist, before you start taking losartan and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually once a day with or without food. Dosage is based on your medical condition and response to treatment.

If you are using the liquid form of this medicine, shake the bottle well before each dose. Carefully measure the dose with a special measuring device / spoon. Do not use a household spoon because you may not get the correct dose.

Use this medicine with the aim of obtaining great benefits and contributions to your health. To help you remember, take it at the same time every day. It is important to continue taking this medicine even if you feel fine. Most people with high blood pressure do not feel sick.

Losartan – Side Effects

Dizziness or lightheadedness may occur as your body adjusts to the medicine. If any of these effects persist or get worse, tell your doctor or pharmacist immediately.

To reduce the risk of dizziness and lightheadedness, get up slowly when getting up from a sitting or lying position. Many people using this medicine do not have serious side effects.

Tell your doctor right away if you have any of these unlikely but serious side effects: fainting, symptoms of high potassium in the blood (such as muscle weakness, slow / irregular heartbeat).

It is necessary to bear in mind that, beyond that losartan may be indicated to prevent kidney problems or treat people who have kidney problems, in rare cases it can also cause serious kidney problems or make them worse. Your doctor will monitor your kidney function while you are taking losartan. Tell your doctor right away if you have any signs of kidney problems, such as a change in the amount of urine.

A very serious allergic reaction to this drug is rare. However, if you develop a rash, itching / swelling (especially of the face / tongue / throat), severe dizziness or shortness of breath, you should notify your doctor immediately.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Losartan – Interactions

Interactions with other drugs can cause serious effects, so you need to be careful about how it works with the combination of other drugs. Keep a list of all the products you use (including prescription and nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicine without your doctor’s approval.

Some products that may interact with this drug include: aliskiren, lithium, drugs that can increase the level of potassium in the blood (such as ACE inhibitors such as benazepril / lisinopril, birth control pills that contain drospirenone).

Some products have ingredients that can raise your blood pressure or make your heart failure worse. Tell your pharmacist what products you are using and ask how to use them safely (especially cough and cold products, dietary supplements, or NSAIDs, such as ibuprofen / naproxen).

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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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