The ketoprofen , is a drug belonging to the anti – inflammatory, antipyretic and analgesic non-steroidal. It is a specialized NSAID-type drug for treatments that relieve pain and treat inflammation. It exerts effects of inhibiting the synthesis of prostaglandins, which avoids affecting them directly and thus achieving a peripheral action on them.

Ketoprofen benefits

Due to its therapeutic qualities, this drug can be used to treat various conditions that produce severe pain and intense acute, subacute or chronic inflammation, which can be fought with the help of ketoprofen.

The use of ketoprofen is used to treat conditions such as:

  • Soothe pain, tenderness, stiffness and swelling that is caused by osteoarthritis as a result of joint deterioration and rheumatoid arthritis caused by inflammation in the joints.
  • It is indicated to relieve some mild ailments such as headaches, migraines, common colds, toothaches, common cold, neurological pain due to rediculalgias, lower the temperature of fever, muscle and back pain.
  • It is used to soften premenstrual pain and during it.
  • It is recommended for treatments for inflammation and ailments related to arthritis, periarthritis, dislocations, tendonitis, joint pain, bursitis, distortions, torticollis, knee injuries, sprains, headaches, low back pain and strains.
  • In many cases, ketoprofen is used to treat ankylosing spondylitis, osteoarthritis, inflammatory rheumatism, juvenile rheumatoid arthritis, Reiter’s syndrome, scapular pain caused by bursitis and gouty arthritis.
  • Injectable ketoprofen is indicated to relieve severe pain caused by renal colic caused by kidney problems.

Ketoprofen is prescribed for the following cases:

In case of fever

This medicine is used as a treatment to lower the temperature in the presence of fever, this is due to its antipyretic properties, which act on the hypothalamus increasing blood flow and thus reducing the temperature.

In case of arthritis and rheumatic problems

Ketoprofen contains great anti-inflammatory benefits, therefore, it serves to treat the problems and discomforts caused by rheumatoid arthritis, it helps to alleviate the pains that are concentrated in the joints due to the suffering of this disease.

In case of menstrual cramps and inflammation of the smooth tissue

Doctors prescribe this drug, to treat female conditions such as dysmenorrhea and other cases of inflammation of biliary, kidney and liver colic. All these conditions will generate severe pain that ketoprofen manages to alleviate.

In case of dental pain

Dentists use ketoprofen to reduce the sensation of pain during dental interventions and recommend it in case of severe pain in the teeth.

In case of pain in the tendons

This drug serves to calm the intensity of pain that is produced by the suffering of tendinitis, it also works effectively by reducing the inflammation and discomfort caused by torticollis.

How ketoprofen is used

  • The drug ketoprofen comes as long-acting capsules, which are taken by mouth.
  • They should generally be taken 3 or 4 times a day in cases of arthritis or every 6 or 8 hours, that will depend on the level of pain or as indicated by the doctor.
  • It is important to take it at the same time throughout the treatment to improve its effectiveness.
  • It can be taken with food to avoid stomach upset.

Ketoprofen commercial presentations

Injectable solution

Each of the vials contains 100 milligrams of ketoprofen accompanied by exipients such as citric acid monohydrate, arginine, 25 milliliters of benzyl alcohol and special water for injections.


In addition to its active ingredient, each capsule contains magnesium extract, talc and lactose.


The tablets are made up of DCI ketoprofen, cornstarch, lactose monohydrate, 40.32 milligrams of powdered sugar, starch, dextrin, magnesium stearate, amberlite, gastro-resistant coatings such as Opadry YP-6-2125, and varnish.


Apart from its main active component which is ketoprofen, each of the suppositories contains solid semisynthetic glycerides and anhydrous colloidal silica.

Ketoprofen Precautions

When starting a treatment with this drug, it is necessary to consult a doctor to avoid and prevent adverse health conditions. Among the most important precautions are:

  • Each ketoprofen tablet contains sucrose and lactose, therefore it is advisable to consult a doctor in case of intolerance to lactose or some sugars before taking it.
  • Ketoprofen injectable solution contains benzyl alcohol, in the case of newborn babies it should be avoided, as it could cause toxic or allergic reactions.
  • This medicine must be taken with care, very high doses and for long periods of time, can increase the risk of a person suffering a stroke or a myocardial infarction.
  • People with high blood pressure or heart failure should inform the doctor, since ketoprokeno often causes fluid retention.

Side effects of ketorpofen

In the event of presenting any of these conditions or symptoms, if you are under ketoprofen treatment, the treating physician should be immediately notified to assess the situation and recommend new indications. Some of those symptoms are:

  • Severe headaches.
  • Diarrhea, bleeding in the stool and flatulence.
  • Dizziness
  • Burning and stomach pain.
  • Constipation.
  • Difficulty to sleep.
  • Edema due to fluid retention.
  • Whistling in the ears.
  • Nervousness.
  • Drowsiness.
  • Sores in the mouth
  • Fever.
  • Itching in the body.
  • Rash or skin eruptions.
  • Blisters
  • Ronquera.
  • Insufficiency of blood pressure.
  • Hives
  • Swelling of the face, eyes, lips, throat, tongue, hands, or arms.
  • Weakness or lack of energy
  • Back pain and excessive tiredness.
  • Pain and difficulty urinating.
  • Lack of appetite.
  • Unusual presentation of bruising and bleeding.
  • Stomach upset
  • Acceleration of the heart rate.
  • Strong pain in the right side of the abdomen.
  • Nausea and vomiting

Ketoprofen contraindications

Like any medicine, ketoprofen contains some contraindications that should be taken into account:

  • If the patient has hypersensitivity to this drug, as well as other analgesics or anti-inflammatory drugs, it is recommended to avoid its use and seek medical help.
  • Ketprofen is not favorable for people with asthmatic conditions, cases of rhinitis, hives, gastrointestinal problems or if you have suffered from internal bleeding.
  • It should be avoided in case of pregnancy and more if they have already passed 3 months of pregnancy.
  • In severe cases of heart failure.
  • It is not recommended for people under 15 years of age.
  • If the person suffers from an ulcer, a perforation in the duodenum in the stomach, persistent and intense pain in the abdomen or black stools, it is advisable not to use ketoprofen, since unfavorable effects could arise.

Conclusion of the use of ketoprofen

To conclude this interesting topic, it can be said that ketoprofen contains many therapeutic qualities to treat numerous conditions accompanied by intense pain and inflammation. This medicine has the ability to soothe ailments caused by rheumatoid arthritis, gout, tendonitis, torticollis, postoperative discomfort, sprains, ankylosing spondylitis and various trauma.

For us it has been a pleasure that you have chosen to read this interesting article. Thanks for choosing us!

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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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