The dexamethasone , is one of the drugs in the group of glucocorticoids and has a very similar effect to the steroid hormone. This drug should be used when the human body does not respond and is usually not able to generate this hormone naturally, which is essential for health.

It has the ability to alleviate all types of inflammations, therefore, it is used to control edema and cure diseases such as arthritis or gastrointestinal, among others.

Specialist doctors administer injectable dexamethasone treatment when they detect problems that affect the blood directly, in the case of thyroid, skin, kidney, eye, nervous system and lung conditions.

It can also be given in low doses, when the person is undergoing chemotherapy, to reduce the symptoms of nausea and vomiting and in cases of organ transplants, so that the human body tries not to reject it.

What is injectable dexamethasone used for?

This medicine can be used to treat various conditions or diseases caused by a deficiency in the production of natural hormones. It can be used in the following situations:

  • Dexamethasone injection can treat different severe allergic reactions, controls fluid retention, as well as inflammations that are concentrated in body tissues due to edema.
  • Treats gastrointestinal diseases and some types of arthritis.
  • This injection is used by doctors to perform diagnostic tests.
  • Dexamethasone is able to fight various conditions of the blood, lungs, sight, epidermis, kidney system, thyroid and emotional states of people.
  • It can be combined with other medications, to diagnose the symptoms generated by low levels of corticosteroids, that is, the lack of production of some substances that the body must produce, which are essential for the proper functioning of the human body.
  • It acts as a treatment for people who have corticosteroid levels below normal levels, this allows steroids to replace their natural production for the body to function properly.
  • The functioning of dexamethisone, attends the conditions of reduction of some inflammations and redness that arise when changing the proper functioning of the immune system.

What is dexamethasone for in pregnancy?

When women are pregnant, they know that any hormonal disorder can bring some consequences that can be irreparable, despite this, obstetrician doctors use injectable dexamethasone frequently in some cases in particular when:

  • There is the possibility of a threat that a premature birth can occur, it allows the placental barrier to be strengthened, it anticipates the maturation process of the premature baby’s lungs, minimizing the risks of complications thereof.
  • Many women suffer from hyperandrogenic syndrome, which is characterized by generating more male than female hormones, therefore, they undergo dexamethasone treatment to avoid miscarriage during their pregnancy.
  • Sometimes it happens that the immune system of the pregnant woman rejects the fetus, the medicine prevents the mother’s immune activity and thus she can have a safe pregnancy.

Injectable dexamethasone precautions

It is important before being injected with dexamethasone, take into account the following:

  • Inform your treating doctor or pharmacist if you are prone to any allergies to any medication, especially dexamethasone.
  • The doctor should be foolish if you are taking other over-the-counter medications, such as vitamins, herbal teas, medicinal supplements, or some other product that you plan to take. The dose of the medications will depend on this and should be observed carefully if any side effects are observed.
  • The doctor should know they have had a history of diseases such as tuberculosis, glaucoma, high blood pressure, cataracts, mental, depressive or emotional problems, herpes, osteoporosis, malaria, muscular conditions, ulcers, liver, heart or intestinal diseases, bacterial infections or disease thyroid.
  • It is very important that the doctor also knows if you are pregnant or breastfeeding.
  • If any type of surgery is to be performed, the surgeon must be aware that the dexamethasone is being injected to take this into account.
  • While under treatment, no type of vaccination is recommended to prevent disease.
  • The injection of this medicine reduces the defenses of the immune system and the ability to eliminate any type of infection, so it is advisable to stay away from people who are sick, especially chickenpox or measles.

Side Effects of Dexamethasone Injection

Although this drug is currently used to fight many diseases, it can cause some negative factors in the body that must be taken into account. Some of these effects are:

Stomach difficulties

When you are under dexamethasone treatment, it is normal for the digestive system to suffer from some alterations such as stomach pain, ulcers in the esophagus or duodenum and constant heartburn.

Gain weight

This happens, since the intake of dexamethasone accelerates anxiety, causing a constant appetite in the person who has this treatment.

Psychiatric deficiency

In some patients, personality disorder problems such as euphoria, irritability, sudden changes in smoke and mania occur.

dermatological problems

This drug can cause certain skin reactions such as acne, severe dry skin, bruising, stretch marks, dermatitis, extreme sweating, hives, and hair loss.

Swelling in the body

This swelling can occur in the joints of the buttocks, armpits and especially in the legs, since it is the lower part of the body.

Decalcification of bones

When the person is under this treatment for a long period, it is very likely that they will start to suffer from osteoporosis.


Catabolism consists of the loss of a high percentage of muscle mass, which can lead to the atrophy of some important muscles.

If accompanied with other medications

In this case, there is a risk of starting to suffer from a disease that was not had before undergoing this treatment.

It is important to know that upon termination of the injectable treatment the side effects may disappear after time passes, if it is noticed that there is no improvement, the doctor must take action and prescribe the necessary treatments to bring the body back to normal.

Conclusion of the use of injectable dexamethasone

In general terms, it can be determined that injectable dexamethasone is a corticosteride that performs the functions of the natural hormone, when the body is not capable of producing said hormone that must be produced by the adrenal glands. If this deficiency occurs, a series of negative factors and diseases can occur that can damage the body and the health of human beings.

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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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