The Flagenase 400 is a drug comprises an antibiotic, the metronidazole and selective amebicidal on Entamoeba histolytica, the diyodohidroxiquinoleína. It is recommended to combat different ailments of bacterial and parasitic origin, among which we can mention amoebic liver abscess and intraintestinal or extraintestinal amebiasis. This medicine is generally used to treat infections caused by certain bacteria. It is most commonly used for abdominal, vaginal, and intestinal infections.
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What is Flagenase 400 for?
Flagenase 400 is useful to combat the proliferation of bacteria in joints and bones. It is also used to attack those bacteria that infect the central nervous system and is very effective against the bacterial infection in the blood, septicemia. In turn, it is used for the following conditions, being very useful in these cases:
Infections: It is used to prevent possible infections infections that occur during colon and intestinal surgeries. This is so since it attacks bacteroides sp, which are the cause of infections in the gums, skin and soft tissues. On the other hand, it is an excellent adjuvant for ulcers and during gastritis.
Parasites in the digestive tract: It is used to treat amoebas inside and outside the intestines. It is also used to combat peritonitis and abscesses in the liver also caused by amoebae. Flagenase 400 also helps against diarrhea that is cheered by the presence of giardia lamblia, a parasite, in the digestive system.
Vaginal infections: These can occur due to the presence of bacteria, fungi and parasites in this area, among which we can mention are those caused by a bacterium called gardnerella vaginalis and vaginal trichomoniasis, which is the sexually transmitted disease that causes trichomonas vaginalis . In addition, it is very effective against nonspecific vaginitis, which is the inflammation that causes infections in the vagina.
Commercial presentation of the Flagenase 400
- Packages of 20 and 30 tablets.
- Packs with 30 capsules
- Packages with 10 vaginal ovules and packages of 10 vaginal capsules
- Injectable solution .
- Oral suspension in 120 ml presentation.
- Pediatric suspension also available in 120 ml bottles.
- Vaginal cream
Side effects of Flagenase 400
Most common side effects of using Flagenase 400
These adverse reactions may be more or less frequent. The most common side effects of using Flagenase 400 that can occur include:
- Headache
- Loss of appetite
- Nausea or vomiting
- Diarrhea
- Acidity
- Cramps in your stomach area
- Constipation
- Metallic taste
These effects may wear off if you stop using the medicine. However, it is recommended that you see your doctor to prevent a more serious condition. Also, if the symptoms do not disappear, you should see a doctor immediately.
Serious side effects of using Flagenase 400
These side effects are not common and you should call your doctor right away if you have these serious side effects. Call 911 if your symptoms are life threatening or if you think you have a medical emergency. Serious side effects can include nervous system effects, including seizures and encephalopathy (abnormal brain function). Symptoms can include:
- Seizures (sudden movements caused by stretching of the muscles)
- Dizziness
- Headache
- Confusion
- Ataxia (loss of control of body movements).
Medicines you should not take with Flagenase 400
Taking metronidazole with certain medications increases the risk of side effects. This is because the amount of either drug can increase in your body. Examples include:
Disulfiram: Do not take disulfiram with metronidazole. Doing so can cause dangerous effects on your body. Its use with metronidazole can cause psychotic reactions. Symptoms can include:
- Confusion
- Hallucinations (seeing or hearing things that are not real)
- Delusions (believing things that are not real)
Do not take metronidazole if you have taken disulfiram in the past two weeks.
Lithium-containing medications or supplements: Increased side effects are related to elevated lithium levels. Your doctor should monitor your lithium levels if you take these medications together.
Warfarin or other blood thinners: Increased side effects of these drugs include an increased risk of bleeding.
Busulfan: If possible, you should avoid taking busulfan with metronidazole. If you take these medicines together, your doctor can check the amount of busulfan in your body more often.
Cimetidine: Taking cimetidine with metronidazole can increase the levels of metronidazole in your body and increase side effects.
Phenytoin or phenobarbital:Taking one of these medications with metronidazole can lower the levels of metronidazole in your body. This could prevent metronidazole from curing your infection.
Flagenase 400 dose:
The dose of Flagenase 400 depends on the condition to be treated. The usual dose of Flagenase 400 in adults is 500 mg orally every 8 hours or twice a day. For the treatment of trichomoniasis, a single dose of 2,000 mg can be taken by mouth after a meal. There are many other dosages depending on the infection being treated, ranging from 250 mg orally 2 times a day to 750 mg orally 3 times a day.
How should I use Flagenase 400?
Here we leave some clarifications for the use of Flagenase 400. Always remember that the best thing to do if you have any questions is to consult your doctor or pharmacist and not self-medicate or increase the dose of your medication if you are not sure which disease affects you or what is the problem that is occurring in your body.
- Flagenase 400 can be taken with or without food . If it causes an upset stomach, it is best taken with food or milk.
- Flagenase 400 vaginal cream or gel is used for vaginal infections. The dose is applied in the vagina usually once or twice a day. Check the package insert or talk to your healthcare provider about how to use the applicator correctly.
- Many things can affect the dose of medicine a person needs, such as body weight, other medical conditions, and other medicines. If your doctor has recommended a different dose than what is provided here, do not change the way you take the medicine without consulting your doctor.
- It is important to take this medicine regularly and exactly as prescribed by the doctor. Keep taking this medicine until the prescription is full, even if you feel better. Since Flagenase 400 is an antibiotic, it is likely that if you stop taking the medicine too soon, the bacteria in question will become stronger and therefore the infection may come back and be more difficult to treat.
- If you miss a dose, take it as soon as possible and continue on your regular schedule. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for the one you forgot. If you are not sure what to do after you miss a dose, ask your doctor or pharmacist.
- Store this medicine at room temperature, protect from light and moisture, and keep out of the reach of children.
- Do not dispose of medicines in sewage (for example, in the sink or toilet) or household waste. Ask your pharmacist how to dispose of medicines that are no longer needed or have expired.
Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.
