The Dalacin C is a drug belonging the group of antibiotics called lincosamides, clindamycin with the active ingredient. It is used to treat infections in different parts of the body, generally caused by sensitive microorganisms, which often do not react to the presence of other antibiotics. In addition, it is used to treat sinus infection, known as acute sinusitis, in children between 1 month and 18 years of age.

Dalacin C uses and dosages

Dalacin C is indicated mainly to treat bacterial infections or infestation caused by certain parasites, its use is extended to the treatment of a series of conditions which you will learn about below:

Infection of the abdominal cavity

The suggested dose varies between 450 and 900 mg intravenously, with intermediate intervals of 8 hours. After the patient stabilizes and is able to tolerate the drug orally, it will be used according to the microbiological sensitivity data. In this case, the appropriate dose would be 450 mg every 6 hours for a period of 3 to 4 weeks as the infection decreases.

Pneumonia

Initially the dose will be 450 to 900 mg intravenously, every 8 hours. After the patient is stable and can tolerate the drug orally, the dose may be 450 mg every 6 hours for a period of time from 10 to 21 days as the patient progresses in his improvement.

Babesiosis

Treatment begins with 1 or 2 g intravenously or 600 mg orally, with a period of 6 to 8 hours, in addition to quinine sulfate 650 mg 3 times during the day for a period of 7 to 10 days.

Osteomielitis

Start with 450 to 900 mg intravenously with intervals of 8 hours in between. Then it will be done orally with a dose that can be 450 mg every 6 hours for a period of 4 to 6 weeks, although there are cases that could increase the time of treatment depending on the severity of the infection.

Deep neck infection

Give the patient 600 mg intravenously every 6 to 8 hours. You can then go to 450 mg orally every 6 to 8 hours for 3 to 4 weeks.

Bacteremia

Start treatment with 450 to 900 mg intravenously every 8 hours. Once the patient reaches greater stability, he can go to 450 mg orally with intervals of every 6 hours for 14 days.

Toxoplasmosis

Treatment begins with 600 mg intravenously or orally every 6 hours. In addition, pyrimethamine will be the adjuvant treatment, which will be administered in a dose of 200 mg orally for once, then it will continue with 50 to 100 mg orally for once a day. However, the role of this antibiotic has not been fully established for the systemic treatment of this condition.

Sinusitis

150 to 300 mg orally with intermediate intervals of 6 hours from 2 to 4 weeks are indicated. The use of Dalacin C is reserved for the treatment of this condition, especially chronic bacterial sinusitis.

Bacterial endocarditis prophylaxis

600 mg will be given 1 hour prior to the procedure orally. For prophylaxis of dental, upper respiratory and esophageal procedures, a single dose is the most appropriate. For patients intolerant to oral treatment, the intravenous route can be used with the same dose, but half an hour before starting the procedure.

Peritonitis

450 to 900 intravenously every 8 hours are indicated. In the case of patients undergoing peritoneal dialysis, the drug will be administered intraperitoneally, a compound dose of 300 mg adding two liters of the liquid used for said dialysis to each one. After stabilizing, you can switch to oral treatment of 450 mg every 6 hours. For this condition the antibiotic must be used in combination with other medications.

Soft tissue or skin infections

Intravenously, 450 to 900 mg will be given every 8 hours. Then they will be 450 mg orally, with intervals of 6 hours for 7 to 10 days or only for 3 days after the acute inflammation disappears. For white tissue infections caused by diabetes, it will be 14 to 21 days.

Vaginosis bacteriana

For 7 days, 300 mg orally twice a day is indicated.

Bacterial infections

Start with 300 to 900 mg IV every 8 hours. After that, it will be 450 mg every 6 hours orally for 7 to 14 days.

Joint infection

Intravenously they will be 450 to 900 mg every 8 hours. After 450 mg orally with intermediate intervals of 6 hours for 3 or 4 weeks.

Malaria

To treat this infection, 900 mg orally will be used, for 5 days and every 8 hours, in addition it must be combined with 650 mg of quinine sulfate every 8 hours for 3 to 7 days.

Some side effects of Dalacin c

  • Rash, sometimes itchy or not.
  • Gastrointestinal disorders, manifested through vomiting, diarrhea, nausea, abdominal pain.
  • Mucosal infections, especially of the mouth or vagina.
  • Altered liver function.
  • Fever, body aches, chills, unusual bleeding from the nose, vagina, mouth, or rectum.
  • Difficulty breathing
  • Swelling of the face, tongue, throat, or lips.
  • Joint pain
  • Throat irritation
  • Alteration of the sense of taste
  • Decrease in white blood cells.
  • Inflammation of the esophagus

Cautions and warnings

  • If the patient suffers from an inflammatory bowel disease, such as ulcerative colitis or Crohn’s disease.
  • In the event that the treatment is extended for a long period of time, it is advisable to perform blood tests in order to assess the blood count as well as the function of the liver and kidney.
  • Long-term use of this drug has been shown to cause other microorganisms to grow, especially fungi.
  • If the patient is under treatment with neuromuscular blocking agents, since the antibiotic could enhance the action of these drugs.

Conclusion.

Dalacin c is an antibiotic prescribed to fight infections caused by bacteria, it is used in cases of sinusitis, peritonitis, pneumonia, skin or soft tissue infections, among other conditions. Clindamycin is its active ingredient. Like any drug, it must be administered under strict medical supervision since its secondary effects can lead to other even more serious diseases.

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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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