We usually hear about the benefits and peculiarities of  Butylhyoscine . Here we tell you all the details.

Butylhyoscine – What is it 

Hyoscine butylbromide, also known as scopolamine butylbromide and marketed under the brand name Buscopan, is a medication used to treat cramp-like abdominal pain, esophageal spasms, kidney colic, and bladder spasms. It is also used to improve respiratory secretions at the end of life. Hyoscine butyl bromide can be taken by mouth, by injection into a muscle, or into a vein.

Butylhyoscine – Origin and sale

It is manufactured from hyoscine that occurs naturally in the deadly nightshade plant.

Each round, white, sugar-coated tablet contains hyoscine butyl bromide 10 mg. Non-medicinal ingredients: acacia, carnauba wax, castor oil, lactose, magnesium stearate, cornstarch, polyethylene glycol, shellac, sucrose, talc, tartaric acid, titanium dioxide and white wax.


Each ml contains hyoscine butyl bromide 20 mg. Non-medicinal ingredients: sodium chloride and water for injections.

Butylhyoscine – Uses

Medical uses

Hyoscine Butyl Bromide is effective in treating crampy abdominal pain. Hyoscine butyl bromide is effective in reducing the duration of the first stage of labor, and is not associated with any obvious adverse outcomes in the mother or neonate.

It is also used during abdominal or pelvic MRI or CT to improve image quality.

Butylhyoscine – Pharmacology

It is a quaternary ammonium compound and a semisynthetic derivative of hyoscine hydrobromide (scopolamine). Binding of the butyl bromide moiety effectively prevents movement of this drug across the blood brain barrier, effectively minimizing undesirable central nervous system side effects associated with scopolamine / hyoscine.

Butylhyoscine – Administration

The usual dose of hyoscine tablets is 1 or 2 10 mg tablets per day. If you need to take this medicine regularly, the usual dose is 1 tablet 3 to 5 times a day. The maximum dose is 6 tablets per day.

For injection, the usual dose is 10 mg to 20 mg given by injection intramuscular (into a muscle), intravenous (into a vein), or subcutaneous (under the skin). The maximum daily dose is 100 mg.

Many things can affect the dose of medicine a person needs, such as body weight, other medical conditions, and other medicines. If your doctor has recommended a different dose than those listed here, do not change the way you are using the medicine without consulting your doctor.

Swallow the tablets whole with a glass of water. Do not crush or chew the tablets. It is important that you use this medicine exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for the one you forgot. If you are not sure what to do after you miss a dose, contact your doctor or pharmacist.

Store this medicine at room temperature, protect from light and moisture, and keep out of the reach of children. Do not dispose of medicines in sewage (for example, in the sink or toilet) or household waste. Ask your pharmacist how to dispose of medicines that are no longer needed or that are no longer valid.

Butylhyoscine – Side Effects

Side effects can include drowsiness, vision changes, glaucoma triggering, and severe allergies. Drowsiness, however, is rare. It is not clear if it is safe in pregnancy. It is an anticholinergic agent, which does not have much effect on the brain.

Because the medication crosses the blood-brain barrier, it has fewer effects on the brain and therefore has a lower incidence of center-mediated effects (such as delusions, drowsiness, and inhibition of motor functions) that impede the usefulness of other anticholinergics. drugs Hyoscine butyl bromide can still affect the chemoreceptor activation zone due to the lack of a well-developed blood-brain barrier in the medulla oblongata, which potentiates the antiemetic effects it produces through local action on the smooth muscle of the gastrointestinal tract.

The following side effects have been reported by at least 1% of people using this medicine. Many of these side effects can be controlled, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist can advise you on managing side effects.

  • Blurred vision that is temporary
  • Constipation
  • Decreased ability to sweat
  • Diarrhea
  • Dizziness
  • Dry mouth
  • Fast heartbeat
  • Redness
  • Nausea

Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you don’t seek medical attention.

Check with your doctor as soon as possible if you experience any of the following side effects:

  • Difficulty urinating
  • Difficulty breathing
  • Skin rash and itching
  • Vision changes

Stop using the medication and seek immediate medical attention if any of the following occur:

  • Painful red eye with loss of vision
  • Symptoms of a severe allergic reaction (such as hives, difficulty breathing, swelling of the face, mouth, tongue, or throat)
  • Some people may experience side effects other than those listed. Check with your doctor if you notice any symptoms that concern you while using this medicine.

Butylhyoscine – Overdose

Hyoscine butyl bromide is not centrally active and has a low incidence of abuse. In 2015, inmates at Wandsworth Prison and other UK prisons were reported to be smoking hyoscine hybrombromide, releasing the potent hallucinogen scopolamine. There have also been reports of abuses at the Mashhad Central Prison in Iran.

It belongs to the group of medicines called antispasmodics. Hyoscine is used to relieve smooth muscle spasms (cramps) in the stomach and intestines, and in the bladder and urethra. Hyoscine reduces spasms by relaxing the smooth muscles of the stomach, intestines, bladder, and urethra. The injection form is used to relieve these same types of muscle spasms that can occur during diagnostic procedures.

Butylhyoscine – Precautions

Your doctor may have suggested this drug for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or you are not sure why you are using this medicine, talk to your doctor. Do not stop using this medicine without consulting your doctor.

Do not give this medicine to anyone else, even if they have the same symptoms as you. It may be harmful for people to use this medicine if your doctor has not prescribed it.

Butylhioscine – Contraindications

You should not use this medicine if:

  • Are allergic to hyoscine or any ingredient in this medicine
  • Are allergic to other atropinics (eg, atropine, scopolamine)
  • Have myasthenia gravis
  • You have megacolon (enlarged colon)
  • Have glaucoma
  • You have obstructive prostatic hypertrophy (enlarged or blocked prostate)

Also, do not use the injection of this medicine if:

  • You are receiving this medicine as an injection into a muscle and are taking a blood thinning medicine (eg, warfarin, heparin)
  • You have a narrowing of the gastrointestinal tract
  • Has a racing heartbeat
  • Have angina
  • Have heart failure
Samantha Robson
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Dr. Samantha Robson ( CRN: 0510146-5) is a nutritionist and website content reviewer related to her area of ​​expertise. With a postgraduate degree in Nutrition from The University of Arizona, she is a specialist in Sports Nutrition from Oxford University and is also a member of the International Society of Sports Nutrition.

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